Actively Recruiting
The Effectiveness of the Deep Rectus Sheath (Preperitoneal) Block for Postoperative Analgesia in Abdominal Surgery A Prospective Observational Clinical Study
Led by San Giovanni di Dio Hospital · Updated on 2026-05-22
60
Participants Needed
2
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying the effectiveness of the Deep Rectus Sheath (Preperitoneal) block in adults undergoing open or laparoscopic abdominal surgery. The goal is to see if this ultrasound-guided pain relief technique improves recovery and controls pain better than standard care or other nerve block methods such as TAP, ESP, or QL blocks. This observational clinical study is non-interventional and focuses on routine clinical care outcomes. Participants will receive pain management as per standard practice, which may include systemic analgesia alone, the Deep Rectus Sheath block combined with standard care, or other fascial plane blocks combined with standard care. Details such as the type of block, timing, technique, and local anesthetic dosages will be recorded. All patients will also receive multimodal pain relief following hospital protocols, with opioids reserved for rescue treatment. During the study, participants' recovery quality will be measured using the Quality of Recovery-15 (QoR-15) score at 24 hours after surgery. Pain levels at rest and with movement will be tracked up to 48 hours, along with analgesic use, time to first pain medication request, mobilization time, and any complications. Safety monitoring includes checking for block-related issues and neurological symptoms up to 7 days after surgery. The study is expected to complete within 12 months.
CONDITIONS
Brief Title
Deep Rectus Sheath (DRS) Block in Abdominal Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Undergoing abdominal surgery, either open or laparoscopic
- ASA physical status I to III
- Receiving neuraxial or general anesthesia as part of standard care
- Able and willing to provide informed consent
You will not qualify if you...
- Refusal to provide informed consent
- Contraindications to locoregional anesthesia
- Known allergy to local anesthetic agents
- Coagulation disorders or incompatible anticoagulant therapy
- Infection at the injection site
- Cognitive impairment preventing reliable outcome assessment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 7 days after surgery
Participants who undergo routine abdominal surgery are observed as part of standard clinical care. Detailed data on analgesic techniques and postoperative recovery are recorded without altering clinical management.
Assessments at predefined time points up to 48 hours postoperatively and follow-up evaluations up to 7 days
Trial Site Locations
Total: 2 locations
1
Crotone Hospital
Crotone, Italy
Not Yet Recruiting
2
Crotone Hospital
Crotone, Italy
Actively Recruiting
Research Team
T
Tommaso Sorrentino, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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