Detection of myocardial damage in patients with sarcoidosis.
Manesh R Patel, Peter J Cawley, John F Heitner...
https://pubmed.ncbi.nlm.nih.gov/19884472Actively Recruiting
Age: 18Years +
All Genders
ID01745237
Detection and Prognostic Significance of Myocardial Damage Visualized by Delayed-Enhancement Cardiovascular Magnetic Resonance in Patients With Sarcoidosis
Led by Duke University · Updated on 2025-04-13
27000
Participants Needed
1
Research Sites
N/A
Total Duration
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AI-Summary
What this Trial Is About
Researchers are studying the use of cardiac magnetic resonance (CMR) imaging to detect heart involvement in patients with sarcoidosis, a condition that can cause serious heart complications and death. The study aims to determine how well CMR identifies heart damage compared to standard clinical evaluations in people with confirmed or suspected cardiac sarcoidosis. This observational study is led by Duke University and focuses on improving understanding of heart risks in sarcoidosis patients. Participants will undergo CMR scans along with their usual clinical assessments to look for heart damage. The study does not involve any treatments but monitors heart health using imaging technology. The goal is to see if CMR can find subtle heart problems that routine evaluations might miss. During the study, participants will be followed for more than one year to track outcomes such as cardiac death, arrhythmic death, and lung-related mortality. Researchers will also observe other events like all-cause mortality, arrhythmic episodes, and the need for heart or lung transplants. This long-term monitoring will help assess the usefulness of CMR in predicting serious health events in sarcoidosis patients.
CONDITIONS
Brief Title
Delayed-Enhancement Cardiovascular Magnetic Resonance in Patients With Sarcoidosis
Who Can Participate
Age: 18Years +
All Genders
Eligibility Criteria
You may qualify if you...
- Biopsy proven sarcoidosis
- Suspected cardiac sarcoidosis
- Age 18 years or older
You will not qualify if you...
- Contraindication to MRI
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Diagnostic Evaluation
Duration - 1 day
Participants undergo cardiovascular magnetic resonance (CMR) imaging to detect cardiac involvement or myocardial damage.
1 visit (in-person)
Long-term Monitoring
Duration - More than 1 year
Participants are monitored for cardiac and pulmonary outcomes over time to assess the prognostic significance of myocardial damage.
Periodic follow-up visits as determined by the study team
Trial Site Locations
Total: 1 location
1
Duke University Medical Center
Durham, North Carolina, United States, 27707
Actively Recruiting
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Research Team
H
Han W Kim, MD
R
Raymond J. Kim, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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