Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
Healthy Volunteers
NCT06471244

Development of Electroencephalography (EEG) and Magnetoencephalography (MEG) Source Reconstruction With Fast Multipole Method

Led by Worcester Polytechnic Institute · Updated on 2025-05-28

30

Participants Needed

2

Research Sites

117 weeks

Total Duration

On this page

Sponsors

W

Worcester Polytechnic Institute

Lead Sponsor

T

Technische Universität Ilmenau

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to learn if an advanced 256 dry electrode EEG cap augmented with MEG readings and coupled with a new high-resolution fast brain modeling software gives a better EEG and MEG source localization in real time. The main questions it aims to answer are: * Does the testbed better localize brain sources for finger movement? * Does the testbed better localize brain sources for median nerve stimulation? * Does the testbed better localize brain sources for speech processing? * Researchers will compare the predicted cortical locations with MEG data and known anatomical locations of the neuronal generators. Participants will: * Undergo Magnetic Resonance Imaging (MRI) scans for brain and head model creation * Undergo three different EEG tests * Undergo three different MEG tests

CONDITIONS

Official Title

Development of Electroencephalography (EEG) and Magnetoencephalography (MEG) Source Reconstruction With Fast Multipole Method

Who Can Participate

Age: 18Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age at least 18 and less than 66 years
  • Normal hearing and (corrected) vision
  • Able to understand and give informed consent
Not Eligible

You will not qualify if you...

  • Cardiac pacemaker or pacemaker wires; neurostimulators; implanted pumps
  • Metal in the body (rods, plates, screws, shrapnel, dentures, IUD) or metallic particles in the eye
  • Surgical clips in the head or previous neurosurgery
  • Any magnetic particles in the body
  • Cochlear implants
  • Prosthetic heart valves
  • History of skull injury or defects
  • Significant claustrophobia; Ménière's disease
  • Pregnancy, breast feeding
  • Neurological or psychiatric diagnoses or medications influencing brain function
  • Current substance abuse (exception: concurrent nicotine use is allowed)
  • Failure to perform the behavioral tasks or psychological evaluation tests
  • Prisoners

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Technical University Ilmenau

Ilmenau, Germany

Actively Recruiting

2

Max-Planck-Institut für Kognitions- und Neurowissenschaften [Cognitive and Neuroscience]

Leipzig, Germany

Actively Recruiting

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Research Team

S

Sergey N Makaroff, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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Development of Electroencephalography (EEG) and Magnetoencephalography (MEG) Source Reconstruction With Fast Multipole Method | DecenTrialz