Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID05447806

Glucose Management Clinical Decision Support to Improve Outcomes in Academic and Community Hospitals

Led by Milton S. Hershey Medical Center · Updated on 2026-05-14

15732

Participants Needed

2

Research Sites

52 weeks

Total Duration

On this page

Sponsors

M

Milton S. Hershey Medical Center

Lead Sponsor

N

National Institutes of Health (NIH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating the impact of an electronic medical record clinical decision support (CDS) tool on controlling abnormal blood sugar levels, known as dysglycemia, in hospitalized patients with diabetes or stress-related hyperglycemia. The study aims to examine how this tool affects clinical outcomes, hospital costs, and healthcare providers' knowledge and practice performance in both academic and community hospital settings. This research involves non-intensive care patients and explores the tool’s influence on improving hospital care delivery and reducing complications related to high glucose. The study uses an innovative alert-CDS tool integrated into the electronic medical record system. This tool automatically identifies dysglycemia and inadequate insulin use, then sends alerts with treatment recommendations to healthcare providers during active phases of the study. The trial alternates between six active 3-month periods when alerts are sent and six inactive 3-month periods without alerts, covering a total of 36 months. During inactive periods, data on care gaps are collected but alerts are not shown. This setup allows comparison between standard care and care supported by the alert-CDS tool. Participants include adult patients hospitalized or receiving ambulatory care at several hospitals within the health system. The study tracks multiple outcomes such as hospital length of stay, glycemic control measures, rates of complications, mortality, hospital resource use, and economic impacts. Provider perspectives and decision-making related to dysglycemia management are also assessed through surveys. The total observation period spans up to three months per hospital admission, with some measures extending up to a year after discharge.

CONDITIONS

Brief Title

Diabetes Clinical Decision Support

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Hospitalized adult (over 18 years) patients at Penn State Health and affiliated hospitals
  • Ambulatory adult (over 18 years) patients at Penn State Health and affiliated hospitals
  • Experience of an alert or disease management message related to blood sugar control
Not Eligible

You will not qualify if you...

  • Children under 18 years of age

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person or via medical record review)

Implementation

Duration - Up to 36 months

Participants are hospitalized patients whose clinical care is observed during alternating 3-month periods when an electronic clinical decision support tool is active or inactive in the medical record.

Continuous monitoring during hospital stay

Long-term Monitoring

Duration - Up to 12 months post discharge

Participants are observed for outcomes such as hospital readmission, glycohemoglobin levels, and mortality up to 12 months after hospital discharge.

Follow-up assessments after discharge as needed

Trial Site Locations

Total: 2 locations

1

Penn State Hershey Medical Center

Hershey, Pennsylvania, United States, 17033

Actively Recruiting

2

Penn State Health St. Joseph Medical Center

Reading, Pennsylvania, United States, 19605

Actively Recruiting

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Research Team

A

Ariana Pichardo-Lowden, MD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

2

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