Actively Recruiting
Double Kissing-crush vs Controlled Balloon-crush Techniques For Complex Coronary Bfurcation Lesions
Led by Istanbul Mehmet Akif Ersoy Educational and Training Hospital · Updated on 2025-04-17
300
Participants Needed
2
Research Sites
91 weeks
Total Duration
On this page
Sponsors
I
Istanbul Mehmet Akif Ersoy Educational and Training Hospital
Lead Sponsor
S
Sisli Hamidiye Etfal Training and Research Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
The Crush technique for coronary bifurcation lesions has evolved significantly since its introduction to the literature by Colombo et al. in 2003, with several iterations, including double kissing balloon inflation. The main disadvantage of the historical Crush technique is the low success rate of the final kissing balloon inflation. An improvement came with the introduction of double kissing crush stenting aiming for the shorter protrusion and kissing balloon dilation performed before and after main branch stent implantation. The double kissing crush provides a significant reduction in major adverse cardiovascular events compared to Provisional stenting, Crush, and Culotte techniques. Recently, a novel modified mini-crush technique (controlled balloon-crush) has been introduced to the literature and is one of the most up-to-date crush techniques. The main advantage of this technique over the contemporary mini-crush technique is that the side branch can be easily rewired, and the 1:1 size non-compliant balloon can easily pass through the crushed stent structure in the ostial part of the side branch. The basic rationale of this is that the crushing of the side branch stent is done in a more controlled manner (by slowly deflation of the side branch stent balloon), and this causes less disruption of the stent cells. To date, no data compares the mid-term outcomes of double kissing crush and controlled balloon-crush stenting techniques in patients with complex coronary bifurcation lesions. Hence, this study aimed to determine the clinical results of double kissing crush and controlled balloon-crush techniques under mid-term follow-up.
CONDITIONS
Official Title
Double Kissing-crush vs Controlled Balloon-crush Techniques For Complex Coronary Bfurcation Lesions
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged >18
- Undergoing PCI with either double kissing crush or controlled balloon-crush technique
- Presence of complex coronary bifurcation lesion (Medina 0.1.1 or 1.1.1)
You will not qualify if you...
- Non-complex bifurcation anatomy
- Bail-out 2-stent procedure (reverse modified mini-crush)
- ST-elevation myocardial infarction
- Cardiogenic shock
- In-stent restenosis
- Previous coronary artery bypass grafting
- Implantation of bare-metal stent
- End-stage hepatic or renal disease
- Life expectancy less than 1 year
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital
Istanbul, Turkey (Türkiye), 33484
Actively Recruiting
2
Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital
Istanbul, Turkey (Türkiye), 33484
Actively Recruiting
Research Team
F
Fatih Uzun, Professor
CONTACT
A
Abdullah Doğan, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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