Selective targeting of trabecular meshwork cells: in vitro studies of pulsed and CW laser interactions.
M A Latina, C Park
https://pubmed.ncbi.nlm.nih.gov/7789416/Actively Recruiting
Led by Barnet Dulaney Perkins Eye Centers · Updated on 2025-04-18
55
Participants Needed
1
Research Sites
4 weeks
Total Duration
Researchers are investigating how the device-assisted procedure DSLT works as a first treatment option for patients newly diagnosed with primary open angle glaucoma POAG. This research focuses on patients who have not received any previous glaucoma treatments and aims to see if DSLT can reduce intraocular pressure IOP effectively, helping to manage the condition without the need for medications. The study is observational and sponsored by Barnet Dulaney Perkins Eye Centers. The intervention involves the use of DSLT, a device-based procedure designed for patients with mild to moderate POAG and IOP between 18 and 26 mmHg. The study specifically includes patients who have not had prior glaucoma treatment such as medication, laser therapy, or surgery. DSLT is being evaluated to determine if it allows patients to maintain good eye pressure control without starting medication. Participants will be monitored over 12 months to assess the success of IOP reduction through DSLT. Researchers will measure the change from pre-treatment baseline IOP and look for other improvements in the disease state. Throughout the study, patients will have assessments to track eye pressure and overall disease progress, helping to understand how well DSLT supports newly diagnosed POAG patients in controlling their glaucoma.
CONDITIONS
DSLT Performance in Treatment-naïve Patients With Newly Diagnosed Open Angle Glaucoma
D
Derek J Arnson, Master of Education
C
Christine Funke, Medical Doctor
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Barnet Dulaney Perkins Eye Centers
Lead Sponsor
Alcon, a Novartis Company
Collaborating Sponsor
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Procedure occurs once at the start of the study
Participants receive the DSLT procedure as their first line treatment for primary open angle glaucoma.
1 treatment visit (in-person)
Duration - 12 months
Participants are monitored for 12 months to assess the success of IOP reduction and other improvements in disease state following the DSLT procedure.
Regular follow-up visits over 12 months
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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M A Latina, C Park
https://pubmed.ncbi.nlm.nih.gov/7789416/Hana L Takusagawa, Ambika Hoguet, Arthur J Sit...
https://pubmed.ncbi.nlm.nih.gov/37702635/Gus Gazzard, Evgenia Konstantakopoulou, David Garway-Heath...
https://pubmed.ncbi.nlm.nih.gov/30862377/Arun Narayanaswamy, Christopher K Leung, Donny V Istiantoro...
https://pubmed.ncbi.nlm.nih.gov/25429421/Barnet Dulaney Perkins Eye Centers
Lead Sponsor
Alcon, a Novartis Company
Collaborating Sponsor