Study of Heart, Brain, and Blood Vessel Interaction in Healthy Adults

What this Trial Is About

This research aims to evaluate autonomic function, cerebral autoregulation, and cortical activity in healthy adult volunteers. The study investigates how these physiological functions relate to psychological aspects, including depressive symptoms, through comprehensive monitoring of cardiac, cortical, vascular, and cerebrovascular signals. Participants will undergo simultaneous monitoring of electroencephalographic, electrocardiographic, blood pressure, respiratory, and transcranial Doppler signals during three 10-minute sessions. These include a resting supine phase, an active standing phase to trigger autonomic reflexes, and an emotional elicitation phase using 40 short video clips to assess psychological response. The total experiment lasts approximately 30 minutes. During the study, participants will be assessed using psychometric tests alongside physiological recordings. Researchers will measure autoregulation index, baroreflex sensitivity, and cortical activity over 36 months. The study involves no masking and includes healthy volunteers aged 18 and older. Data collected aim to deepen understanding of cardiovascular and cerebral interactions under different conditions.

Dynamic Cardio-vascular, Cerebro-vascular and Cortical Interaction in Healthy Adult Subjects