Actively Recruiting

Age: 16Years +
All Genders
NCT06794827

Early-access Avacopan in Real-world ANCA-associated Vasculitis

Led by Leiden University Medical Center · Updated on 2025-01-27

100

Participants Needed

1

Research Sites

165 weeks

Total Duration

On this page

Sponsors

L

Leiden University Medical Center

Lead Sponsor

U

University of Udine

Collaborating Sponsor

AI-Summary

What this Trial Is About

The current study proposal aims to investigate the clinical practice variation of the initial use of avacopan for AAV patients in Europe. The study will describe patient characteristics and organ-specific clinical benefit of avacopan treatment in a unique, first-experience cohort of AAV patients. By studying the clinical practice variation of first-experience avacopan treatment, this study will be uniquely positioned to identify pivotal issues on the real-life implementation of avacopan treatment. These observational data can ultimately serve to address current knowledge gaps on avacopan treatment in AAV patients, improve the care and drug-access for AAV patients with avacopan treatment and generate new areas of research.

CONDITIONS

Official Title

Early-access Avacopan in Real-world ANCA-associated Vasculitis

Who Can Participate

Age: 16Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Established diagnosis of granulomatosis with polyangiitis (GPA) or microscopic polyangiitis (MPA)
  • Initiation of treatment with avacopan
  • Provided informed consent for use of medical data
Not Eligible

You will not qualify if you...

  • No active ANCA-associated vasculitis disease activity supported by clinical measures or assessments
  • Participant is younger than 16 years old

AI-Screening

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Trial Site Locations

Total: 1 location

1

Leiden University Medical Center

Leiden, Netherlands

Actively Recruiting

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Research Team

Y

Y.K.O. Teng, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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