Effect of Early Combined Motor and Cognitive Training on Recovery in Adults With Aneurysmal Subarachnoid Hemorrhage

What this Trial Is About

Researchers are investigating the effects of early motor-cognitive integrative training e-MCIT on cognitive and motor recovery in patients who have experienced aneurysmal subarachnoid hemorrhage aSAH, a type of stroke caused by aneurysm rupture. This condition often leads to post-stroke cognitive impairments affecting memory, attention, executive function, and language, which impact patients ability to perform daily activities and return to work. The study aims to better understand how combining motor and cognitive therapy soon after stroke can improve these outcomes compared to traditional early mobilization therapy. The study randomly assigns 18 adult patients with confirmed aSAH and cognitive impairment to either the e-MCIT group or a traditional early mobilization group. The e-MCIT involves simultaneous motor and cognitive training sessions lasting 30 minutes, 4-5 times per week until hospital discharge, while the traditional group receives motor-only training following a staged rehabilitation protocol. Both groups receive additional occupational and speech therapy as needed. The intervention starts in the intensive care unit ICU and continues through the subacute hospital phase. Participants undergo assessments at baseline, ICU discharge about 2 weeks, hospital discharge about 4 weeks, 3 months, and 1 year after intervention start. Evaluations include cognitive tests like the Montreal Cognitive Assessment, motor function scales, brain activity monitoring with functional near-infrared spectroscopy, and measures of daily living abilities, mood, and quality of life. Researchers will analyze changes over time to determine how the interventions impact cognitive and motor recovery, functional independence, and long-term reintegration into work and daily activities.

Early Motor-Cognitive Integrative Training on Cognitive and Motor Performance in Patients With Aneurysmal Subarachnoid Hemorrhage