Do Dietary Patterns Influence Your Weight Management and Circadian Rhythms?

What this Trial Is About

Researchers are investigating how different dietary compositions affect the body's internal biological rhythms, specifically focusing on food intake timing, appetite regulation, and energy expenditure patterns. The study aims to explore the link between diet and weight management, with an overarching goal to provide evidence that could inform dietary interventions to address obesity. Participants will undergo two dietary interventions in random order, referred to as Dietary A and Dietary B, in a single-blind format where details of each diet are withheld during recruitment. The study includes both field-based dietary phases where standard meals are provided and inpatient stays with further controlled meal provision. During these periods, participants will record their food intake daily in real time. Throughout the study, frequent blood draws will be conducted alongside collection of urine, saliva, and stool samples to monitor various biological rhythms, including melatonin and energy expenditure. Key outcomes measured are the timing and amount of caloric intake in the evening and the circadian phase of melatonin rhythm. The entire process includes detailed assessments to understand how diet influences weight and circadian biology over the study period.

Eating to Adjust the Timing System