Actively Recruiting
Effect of a High-Protein, High-Fiber Pre-Fast Meal on Satiety and Glycemic Profiles During Fasting: A Randomized Crossover Study
Led by King Faisal University · Updated on 2026-03-12
38
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
K
King Faisal University
Lead Sponsor
S
Saudi Food and Drug Authority
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are investigating how a high-protein, high-fiber meal eaten before fasting affects feelings of fullness and blood sugar levels during fasting hours in healthy adults. This randomized crossover study compares a standardized high-protein, high-fiber pre-fast meal to a low-protein, low-fiber meal guided by dietary instructions, aiming to understand their impact on appetite and glycemic responses. Participants will complete two study periods, each lasting two consecutive days, with a three-day break in between. In one period, they will consume a provided high-protein, high-fiber meal including oats, Greek yogurt, peanut butter, dried cranberries, and almonds. In the other period, they will follow written instructions to consume a low-protein, low-fiber pre-fast meal without calorie limits. Throughout the study, participants' feelings of hunger, fullness, desire to eat, and anticipated food intake will be measured at specific times during fasting. Blood sugar levels will be continuously monitored using a glucose monitor. Researchers will analyze the relationship between glucose changes and appetite sensations. The study includes fasting, meal consumption, monitoring, and washout phases to thoroughly evaluate effects.
CONDITIONS
Brief Title
Effect of a High-Protein, High-Fiber Pre-Fast Meal on Satiety and Glycemic Profiles During Fasting
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years and older
- Willingness to comply with study procedures, including fasting and continuous glucose monitoring
- Ability to provide informed consent
You will not qualify if you...
- Diagnosed diabetes mellitus or known metabolic disease
- History of cardiovascular, gastrointestinal, or endocrine disorders that may affect study outcomes
- Use of medications known to affect glucose metabolism or appetite
- Pregnancy or lactation
- Known allergy or intolerance to any study meal components (oats, dairy, peanuts, nuts, cranberries)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 7 to 9 days
Participants complete two dietary intervention conditions in a randomized sequence: consuming a high-protein, high-fiber pre-fast meal for two consecutive days and following a low-protein, low-fiber pre-fast meal for two consecutive days, separated by a three-day washout period.
Multiple visits on intervention days for meal consumption and assessments
Duration - Up to 2 days per intervention condition
Participants' subjective appetite sensations and glycemic profiles are monitored continuously during each intervention condition to assess effects during fasting hours.
Continuous glucose monitoring throughout fasting periods; subjective appetite assessments at specific times daily
Trial Site Locations
Total: 1 location
1
King Faisal University
Al-Ahsa, Eastern Province, Saudi Arabia, 31982
Actively Recruiting
Research Team
W
Wafa Alotaibi
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
PREVENTION
Number of Arms
2
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