Eating Disorders Genetics Initiative 2 Studying Genetics of Anorexia, Bulimia, Binge-Eating, ARFID, and Controls

What this Trial Is About

The Eating Disorders Genetics Initiative 2 EDGI2 aims to increase the number, diversity, and types of eating disorder cases studied. Researchers are enrolling 20,000 new participants across several countries, including the US, Mexico, Australia, New Zealand, Sweden, and Denmark. This study focuses on people with different eating disorders such as anorexia nervosa, bulimia nervosa, binge-eating disorder, and avoidant restrictive food intake disorder, as well as control participants without eating disorders. The goal is to better understand eating disorders and how they relate to each other to help develop improved treatments. Participants are grouped based on their self-reported lifetime history of eating disorders or no history of disordered eating behaviors. This is an observational study, so no active treatment is given. Instead, participants complete a series of questionnaires and provide saliva samples for genetic analysis. The study seeks to include at least 30% of participants from underrepresented groups to enhance diversity. During the study, participants provide information about their eating disorder history, mental health, mood, substance use, life events, quality of life, exercise habits, and perfectionism through questionnaires. Researchers collect saliva samples for genotyping. The primary outcomes include the number of participants identified with each eating disorder and the age when the disorder began. The study is designed to last until 2027, with participant involvement mainly involving completing questionnaires and providing samples.

Eating Disorders Genetics Initiative 2