Actively Recruiting
Effect of Bariatric Surgery on Cardiac Function in Patients With Hypertension
Led by Beijing Friendship Hospital · Updated on 2025-02-13
40
Participants Needed
1
Research Sites
25 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to investigate how bariatric surgery affects heart function, particularly in patients with hypertension. Obesity, a widespread chronic metabolic disease, contributes to cardiovascular risks such as high blood pressure and can impact heart structure and function over time. The study compares the effects of two types of bariatric surgeries, laparoscopic sleeve gastrectomy (LSG) and Roux-en-Y gastric bypass (RYGB), on cardiac function assessed by echocardiography in patients with hypertension. Participants will undergo either LSG or RYGB surgery along with medical treatment to manage cardiovascular risks like hypertension, diabetes, or dyslipidemia. The study observes how these surgeries influence heart function and structure, with a focus on changes in left ventricular ejection fraction and diameter over time. The two groups are followed up to evaluate the outcomes related to cardiac health and medication use. During the study, participants will have regular assessments including echocardiography to measure heart function changes at 12 and 24 months. Researchers will monitor major adverse cardiac events, blood pressure, and the number of antihypertensive medications required. The study involves careful observation of heart function changes after surgery to understand the impact of bariatric procedures on hypertension management over two years.
CONDITIONS
Brief Title
Effect of Bariatric Surgery on Cardiac Function in Patients With Hypertension
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 70 years
- Body mass index (BMI) greater than 24 kg/m2
- Patients who have undergone bariatric surgery at Beijing Friendship Hospital
- History of hypertension treated with two or more antihypertensive drugs for more than 4 weeks
- Able to provide written informed consent without major barriers
You will not qualify if you...
- Secondary hypertension, except due to sleep apnea
- Cardiovascular disease such as myocardial infarction, heart failure, stroke, or coronary revascularization within the past 6 months
- Severe concomitant diseases including autoimmune disease, malignancy, late-stage liver disease, respiratory or digestive diseases
- Unable to understand or follow study procedures
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Surgery day and immediate recovery period
Participants undergo bariatric surgery, either laparoscopic sleeve gastrectomy (LSG) or Roux-en-Y gastric bypass (RYGB), along with medical treatment to manage cardiovascular risks including hypertension.
1 hospital admission for surgery and immediate post-operative care
Duration - Up to 24 months
Participants attend follow-up visits to monitor cardiac function and health status after surgery.
Multiple follow-up visits over 12 to 24 months
Trial Site Locations
Total: 1 location
1
Beijing Friendship Hospital, Capital Medical University
Beijing, Beijing Municipality, China, 100050
Actively Recruiting
Research Team
R
Rongchong Huang, M.D.
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here