Effectiveness and Safety of Platelet-rich Plasma Injection for Treating Knee Osteoarthritis and Nearby Tissue Injuries

What this Trial Is About

Researchers are evaluating the safety and effectiveness of platelet-rich plasma PRP injection therapy to treat knee osteoarthritis and injuries to the surrounding soft tissues. This single-center exploratory study aims to provide a more reliable basis for treating joint injuries by comparing PRP injections to sodium hyaluronate injections. Participants receive injections either with PRP or with sodium hyaluronate into the joint cavity. The study includes different postoperative time points at 6 weeks and 3 months for treatment assessments. Imaging tests such as X-rays, CT scans, and MRI are performed before treatment, 3 weeks after, and 6 months after treatment to monitor changes. During the study, participants undergo comprehensive clinical and imaging examinations to evaluate their joint condition. Researchers collect imaging data at multiple time points to measure treatment effects. The study requires informed consent and monitors participants for safety and effectiveness throughout the treatment and follow-up periods, which continue up to 6 months post-treatment.

Effect of Platelet-rich Plasma (PRP) Injection on Knee Osteoarthritis