Actively Recruiting
Evaluation of Clinical-functional and Radiographic Outcomes in Patients Who Underwent Meniscal Allograft Transplantation (MAT) at 10 Years
Led by Istituto Ortopedico Rizzoli · Updated on 2025-08-06
397
Participants Needed
1
Research Sites
N/A
Total Duration
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AI-Summary
What this Trial Is About
Researchers are studying meniscal allograft transplantation (MAT) as a treatment for post-meniscectomy syndrome in patients who have had meniscal injuries and surgeries. Menisci are important cartilage structures in the knee that help with load transmission and stability, protecting against osteoarthritis. This observational study aims to evaluate clinical, functional, and radiographic outcomes of patients who underwent MAT at least 10 years ago to better understand the long-term effects on knee osteoarthritis. The study focuses on patients who had a meniscal transplant at the Rizzoli Orthopedic Institute at least 10 years prior. There are no interventions or treatments given during the study as it observes existing patients. The research collects data on knee function and osteoarthritis progression over a long follow-up period, using tools such as the Lysholm Knee Score and Kellgren-Lawrence scale to assess outcomes. Participants will be evaluated through clinical-functional assessments and radiographic controls after 10 years from their surgery. Outcome measures include knee function scores, pain levels, activity ratings, and osteoarthritis severity. The study involves reviewing these measures to understand the durability and protective effects of MAT on knee joints. Results will help inform the long-term benefits and risks of meniscal transplantation in patients with previous meniscal injuries.
CONDITIONS
Brief Title
Evaluation of Clinical-functional and Radiographic Outcomes in Patients Who Underwent Meniscal Allograft Transplantation (MAT) at 10 Years.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged between 18 and 65 at the time of surgery
- Both male and female
- Patients who underwent meniscal transplantation at the Rizzoli Orthopedic Institute at least 10 years ago
You will not qualify if you...
- Patients who do not give consent to be included in the study
- Patients who are no longer reachable
- Presence of infection or hematologic, rheumatic, or coagulation disorders at the time of evaluation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Single timepoint at 10 years post-surgery
Participants who underwent meniscal allograft transplantation are assessed for clinical-functional and radiographic outcomes 10 years after surgery.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
IRCCS Istituto Ortopedico Rizzoli
Bologna, Italy, 40136
Actively Recruiting
Research Team
S
Stefano Zaffagnini
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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