Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
NCT06236503

Effect of Transcranial Direct Current Stimulation in Altered States of Consciousness

Led by IRCCS Centro Neurolesi Bonino Pulejo · Updated on 2025-05-01

100

Participants Needed

1

Research Sites

155 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Transcranial Direct Current Stimulation (tDCS) is a non-invasive, painless brain stimulation treatment that uses low-intensity direct electrical currents to stimulate specific parts of the brain. Transcranial Direct Current Stimulation (tDCS) can both facilitate anodic stimulation and inhibit cathodic stimulation specific brain areas since many neurological and psychiatric disorders are connected to hypoactivity or hyperactivity in specific areas of the nervous system. This phenomenon is based on two processes: the reorganization of functional neural circuits and their reconstruction. In light of the studies mentioned above, it is presumed that Transcranial Direct Current Stimulation (tDCS) can be a valuable tool to facilitate the process of neuroplasticity in individuals with chronic neurological diseases and in patients with impaired consciousness following severe brain injury. A previous study demonstrated that a single session of transcranial direct current electrical stimulation could temporarily improve signs of consciousness in patients in a minimally conscious state (MCS)

CONDITIONS

Official Title

Effect of Transcranial Direct Current Stimulation in Altered States of Consciousness

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients diagnosed with a minimally conscious state
  • Written informed consent obtained from a family member
Not Eligible

You will not qualify if you...

  • Patients currently in coma
  • Patients with metallic brain implants
  • Patients who have had a craniotomy
  • Patients with a pacemaker

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

IRCCS Centro Neurolesi Bonino Pulejo

Messina, Italia, Italy, 98124

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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