Stress and the reproductive axis.
D Toufexis, M A Rivarola, H Lara...
https://pubmed.ncbi.nlm.nih.gov/25040027Actively Recruiting
Led by Fakultas Kedokteran Universitas Indonesia · Updated on 2024-07-26
75
Participants Needed
1
Research Sites
26 weeks
Total Duration
Researchers are investigating whether Cognitive Behavioral Therapy (CBT) can improve psychological, neurological, and hormonal factors in women undergoing In Vitro Fertilization (IVF). The study seeks to determine if CBT can reduce anxiety, depression, and improve coping mechanisms as well as influence hormone levels like cortisol, norepinephrine, and free triiodothyronine in this group. The study is randomized and compares CBT to no intervention to evaluate these psycho-neuro-endocrine aspects. Participants will attend eight weekly appointments where they will either receive structured CBT or no intervention. Psychological assessments including anxiety, depression, and coping mechanisms will be conducted before the first appointment and during the 3rd, 6th, and 8th sessions. Hormone levels will also be measured at these same time points to track changes over the IVF program. Throughout the study, participants' psychological and hormonal changes will be closely monitored at baseline and during the IVF process at several intervals. The main outcomes focus on improvements in anxiety and depression scores, coping skills, and hormone levels measured at baseline and at 3 and 5 weeks into the IVF program. The total participation period covers these assessments alongside the therapy or no intervention sessions, with safety and progress continuously evaluated.
CONDITIONS
Effectiveness of CBT in Improving Psycho-Neuro-Endocrine Factors in Women Following In Vitro Fertilization Program
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You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 8 weeks
Participants attend 8 weekly appointments to receive Cognitive Behavioral Therapy or no intervention, with assessments of psychological and biochemical factors at specified sessions.
8 weekly visits (in-person)
Total: 1 location
1
Cipto Mangunkusumo Hospital
Jakarta Pusat, DKI Jakarta, Indonesia
Actively Recruiting
F
Feranindhya Agiananda
A
Artasya Karnasih
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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