Actively Recruiting

Phase 2
Phase 3
Age: 20Years - 60Years
All Genders
Healthy Volunteers
NCT06453304

Effectiveness of Glycyrrhizin as Intracanal Medication in Root Canal Disinfection and Inflammatory Cytokines

Led by Mansoura University · Updated on 2024-07-03

36

Participants Needed

1

Research Sites

120 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The objective of this study is to investigate "clinically" the effectiveness of Glycyrrhizin based intracanal medication compared to the commonly used intracanal medicaments (calcium hydroxide Ca(OH)2 and Ledermix) on the levels of bacteria and inflammatory cytokines in root canals and periradicular tissues of teeth with apical periodontitis.

CONDITIONS

Official Title

Effectiveness of Glycyrrhizin as Intracanal Medication in Root Canal Disinfection and Inflammatory Cytokines

Who Can Participate

Age: 20Years - 60Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Single-rooted tooth with pulp necrosis and apical periodontitis
Not Eligible

You will not qualify if you...

  • Receiving antibiotic treatment within the preceding 3 months
  • Reporting systemic disease
  • Teeth that could not be isolated with rubber dam
  • Teeth with periodontal pockets deeper than 3 mm

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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2
3
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Trial Site Locations

Total: 1 location

1

Alaa Reda Mohamed Eltantawi

Al Mansurah, Egypt

Actively Recruiting

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Research Team

A

Alaa Eltantawi, phD

CONTACT

G

Ghada Abdelrazik

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

3

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