Actively Recruiting
Effects of Daily Beef Intake, as a Component of a Heart-Healthy Diet on Cellular Zinc
Led by University of California, Davis · Updated on 2026-02-09
20
Participants Needed
1
Research Sites
221 weeks
Total Duration
On this page
Sponsors
U
University of California, Davis
Lead Sponsor
N
National Cattlemen's Beef Association, a contractor to the Beef Checkoff
Collaborating Sponsor
AI-Summary
What this Trial Is About
The objective of the current study is to test the overarching hypothesis that the beef nutritive matrix is uniquely suited to direct dietary zinc to cellular compartments for improved metabolic function, leading to a greater effect on health outcomes. Specifically, whether beef, as a component of a healthy meal, will promote the absorption of zinc into cells, where the zinc will have greater effects on zinc-dependent metabolic processes supporting cardiovascular health. To maximize the observability of these beef-related effects, individuals who are 55- to 70-year-old who generally have a higher risk of zinc deficiency and cardiovascular disease will be enrolled.
CONDITIONS
Official Title
Effects of Daily Beef Intake, as a Component of a Heart-Healthy Diet on Cellular Zinc
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or postmenopausal female aged 55 to 70 years
- Women must have had no menstrual periods for at least two years
- Willing and able to comply with all study protocols and procedures
- Stable dose of prescribed medications for at least 6 months
- Body mass index (BMI) between 18.5 and 29.9 kg/m2
You will not qualify if you...
- Use of daily anticoagulation agents including aspirin or NSAIDs
- Use of prescribed metformin, statins, or medications affecting zinc, protein, or lipid metabolism
- Following vegan, vegetarian, food faddist, or non-traditional diets (e.g. Atkins, Keto, Paleo)
- Consuming 3 or more cups of fruit per day
- Regular consumption of strawberries 2-3 servings per week
- Consuming 4 or more cups of vegetables per day
- Drinking 3 or more cups of coffee or tea per day
- Eating 3 or more ounces of dark chocolate per day
- Alcohol intake exceeding 2 drinks per day for men or 1 drink per day for women
- Restriction of physical activity due to chronic health conditions
- Routine high intensity exercise
- Diagnosis of diabetes
- Blood pressure 140/90 mm Hg or higher
- History of renal or liver disease
- History of heart disease including cardiovascular events or stroke
- Peripheral artery disease or Raynaud's syndrome
- Inability to properly wear PAT probes or abnormal pre-screening PAT measurements
- Cancer diagnosis within the past 5 years
- Malabsorption
- Unwillingness to stop supplement use six weeks before study start
- Smoking, vaping, or cannabis use
- Currently enrolled in another clinical research study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of California, Davis; Department of Nutrition
Davis, California, United States, 95616
Actively Recruiting
Research Team
R
Roberta R Holt, PhD
CONTACT
A
Andrew Hall, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
PREVENTION
Number of Arms
2
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