Studying Breathing Problems in Adults With Obesity and Testing Inspiratory Muscle Training to Help Improve Lung Function

What this Trial Is About

Researchers are studying the respiratory function and inflammation caused by obesity and exploring whether inspiratory muscle training IMT can reduce respiratory system dysfunction. This study focuses on adults aged 30 to 60 who have obesity. The project aims to understand how obesity affects breathing and whether IMT can improve respiratory health. Participants will be randomly assigned to one of three groups an experimental IMT group, a placebo-IMT group, or a control group with no intervention. The experimental group will perform IMT with increasing resistance starting at 30% of their maximum inspiratory pressure, training twice daily for six weeks. The placebo group will do simulated IMT with a fixed low load once daily for six weeks. The control group will not complete the IMT cycle. During the study, participants will undergo pulmonary function tests, respiratory muscle strength assessments, forced oscillation technique measurements, and laboratory tests at the start and after six weeks. Secondary measures include body composition analysis, quality of life questionnaires, and physical activity assessments. The study includes careful monitoring of participants respiratory condition and inflammation markers throughout the trial period.

Assessment of Respiratory Dysfunction in Obesity and the Use of IMT.