Actively Recruiting

Phase Not Applicable
Age: 18Years - 50Years
All Genders
Healthy Volunteers
ID06800833

Effects of Mango or Low-Fat Cookie Consumption on Gut Health, and Its Relationship With Mental, Sexual and Skin Health

Led by San Diego State University · Updated on 2026-01-30

60

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are investigating how eating fresh mango affects the gut microbiome and its connection to skin, sexual, and mental health in generally healthy adults. This study focuses on adults between 18 and 50 years old and aims to understand these relationships through a controlled dietary intervention. Participants are randomly assigned to consume either mango or low-fat cookies daily to compare their effects on various health indicators. Participants will consume 100 calories of either low-fat cookies or mango each day for four weeks. These two groups allow researchers to evaluate and compare how mango versus a low-fat cookie impacts gut health and related areas such as skin hydration, mental well-being, and sexual health. The study does not include blinding, meaning participants and researchers know which group each participant is in. During the study, participants will complete questionnaires assessing sexual and mental health at the start and after four weeks. Skin hydration will be measured at baseline, immediately after product application, and after four weeks. The diversity of the gut microbiome will also be analyzed at the start and after the intervention. This research is sponsored by San Diego State University and will continue through December 2027.

CONDITIONS

Brief Title

Effects of Mango or Low-Fat Cookie Consumption on Gut Health, and Its Relationship With Mental, Sexual and Skin Health

Who Can Participate

Age: 18Years - 50Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Generally healthy subjects
  • Body mass index between 20 and 40 kg/m2
  • Adults aged 18 to 50 years
Not Eligible

You will not qualify if you...

  • Current smoker
  • Pregnant woman
  • Required use of antibiotics
  • Required use of dietary supplements
  • Required medication for metabolic disorders, mental health, or sexual health
  • Allergy to mango or wheat

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 4 weeks

Participants consume either 100 kcal of low-fat cookies or 100 kcal of mango daily to assess effects on sexual, mental, skin, and gut health.

1 baseline visit and 1 follow-up visit

Treatment

Duration - 4 weeks

After a crossover, participants switch to the other intervention (mango or low-fat cookies) for assessment.

1 baseline visit and 1 follow-up visit

Trial Site Locations

Total: 1 location

1

San Diego State University

San Diego, California, United States, 92182

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

PREVENTION

Number of Arms

2

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Frequently Asked Questions

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