Actively Recruiting
The Effects of Performing a Motor Imagery Task on Cortical Excitability During Acute Experimental Muscle Pain and Acute Itch
Led by Aalborg University · Updated on 2024-11-22
30
Participants Needed
2
Research Sites
117 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this project is to determine the effects of performing a motor imagery task on cortical excitability during acute experimental muscle pain (induced by hypertonic saline), acute histaminergic itch (induced by histamine), and non-histaminergic itch stimulation (triggered by Cowhage). We hypothesize that motor imagery will counteract the alterations in cortical excitability observed during experimental muscle pain and both itch models.
CONDITIONS
Official Title
The Effects of Performing a Motor Imagery Task on Cortical Excitability During Acute Experimental Muscle Pain and Acute Itch
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy men and women
- Aged 18 to 60 years
- Speak and understand English
You will not qualify if you...
- Pregnancy or lactation
- Drug addiction including cannabis, opioids, or other addictive drugs
- History of neurological, immunological, musculoskeletal, cardiac, or psychiatric disorders that may affect results
- Current use of medications like antihistamines, antipsychotics, painkillers, or steroids
- Skin diseases such as atopic dermatitis, pruritus nodularis, eczema, or psoriasis
- Moles, scars, or tattoos in the treatment or test area
- Alcohol or painkiller consumption 24 hours before and during study days
- Acute or chronic pain
- Unable to pass Transcranial Magnetic Stimulation Adult Safety Screen
- Contraindications to TMS, including epilepsy or metal implants in head or jaw
- Presence of implanted hearing aids or metal implants on face, including permanent makeup or tattoos
- Participation in other trials within one week (four weeks for pharmaceutical trials)
- Lack of ability to cooperate
AI-Screening
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Trial Site Locations
Total: 2 locations
1
Aalborg University
Gistrup, Denmark, 9260
Actively Recruiting
2
Aalborg University
Gistrup, Denmark, 9260
Actively Recruiting
Research Team
S
Silvia Lo Vecchio
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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