Actively Recruiting

Phase Not Applicable
Age: 18Years - 55Years
All Genders
ID07582718

Effects of a Whole-body High-intensity Interval Training on Cardiorespiratory Fitness, Musculoskeletal Fitness, Body Composition and Blood Parameters in Overweight Subjects

Led by Université Libre de Bruxelles · Updated on 2026-05-13

40

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the effects of a supervised whole-body high-intensity interval training (WB-HIIT) program on physical fitness and health outcomes in adults who are overweight or obese. This study aims to understand whether WB-HIIT, a time-efficient and equipment-free exercise using body-weight movements performed at high intensity, can improve cardiorespiratory fitness, muscular strength, body composition, and metabolic health in adults aged 18 to 55 years with a BMI between 25 and 35 kg/m². Participants are divided into two groups: one group undergoes a 10-week supervised WB-HIIT program with 2 to 3 sessions per week, each lasting 35 to 50 minutes and including 8 to 12 exercises such as squats, lunges, and mountain climbers performed in intervals with controlled recovery. The sessions are led by trained exercise professionals who monitor heart rate and perceived exertion to adjust intensity and progression. The control group maintains their usual lifestyle without structured exercise but completes the same assessments. Throughout the study, participants undergo comprehensive evaluations before and after the intervention, including body composition analysis by DXA, blood tests for metabolic markers, muscle strength testing, and fitness assessments such as a graded treadmill test to measure peak oxygen consumption (VO₂peak) and functional tests like chair-stand, arm-curl, and 6-minute walk tests. Dietary intake and physical activity levels are also recorded. The study measures changes in VO₂peak and muscle strength as primary outcomes, with additional assessments of body composition, metabolic health, and functional capacity. The total participation duration is approximately 10 weeks with evaluations at baseline and after the last training session.

CONDITIONS

Brief Title

Effects of Whole-Body High-Intensity Interval Training on Fitness in Overweight Adults

Who Can Participate

Age: 18Years - 55Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 to 55 years
  • Body mass index (BMI) between 25 and 35 kg/m²
  • Able to provide written informed consent
  • Able to safely participate in high-intensity interval training
  • For participants with BMI > 30 kg/m²: medical clearance from their general practitioner
Not Eligible

You will not qualify if you...

  • BMI < 25 or > 35 kg/m²
  • Presence of any chronic medical condition other than overweight/obesity
  • Known cardiovascular, metabolic, respiratory, or musculoskeletal disease that contraindicates high-intensity exercise
  • Pregnancy
  • Inability to perform exercise testing or complete the WB-HIIT program
  • Any condition judged by investigators to interfere with participation or data interpretation

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Outpatient Treatment

Duration - 10 weeks

Participants in the intervention group complete a supervised whole-body high-intensity interval training (WB-HIIT) program consisting of 2 to 3 sessions per week for 10 weeks. Each session includes 8 to 12 body-weight exercises performed at high intensity with recovery intervals. Progression is achieved by adjusting exercise complexity, sets, and work-to-rest ratio. Participants in the control group maintain their usual lifestyle without structured exercise training.

2 to 3 sessions per week (in-person)

Post-intervention Assessment

Duration - 1 week

Participants undergo comprehensive evaluations including cardiorespiratory fitness, muscular strength and endurance, body composition, functional performance, blood biomarkers, physical activity, and dietary intake. These assessments occur within 72 hours after the last training session or equivalent time for control participants.

1 to 2 visits (in-person)

Trial Site Locations

Total: 1 location

1

Université libre de Bruxelles (ULB)

Brussels, Belgium

Actively Recruiting

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Research Team

J

Julie Carpentier, PhD

M

Malgorzata Klass, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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Published Research Related To This Trial

Effectiveness of Whole-Body High-Intensity Interval Training on Health-Related Fitness: A Systematic Review and Meta-Analysis.

Corentin Scoubeau, Bruno Bonnechère, Miriam Cnop...

https://pubmed.ncbi.nlm.nih.gov/35954911

Body composition, cardiorespiratory fitness, and neuromuscular adaptations induced by a home-based whole-body high intensity interval training.

Corentin Scoubeau, Julie Carpentier, Stéphane Baudry...

https://pubmed.ncbi.nlm.nih.gov/36970125