Study on Carbohydrate Loading Before Heart Surgery in Type 2 Diabetic Patients Undergoing On-Pump Coronary Artery Bypass Surgery

What this Trial Is About

Researchers are evaluating the effects of carbohydrate loading before surgery in diabetic type 2 patients undergoing coronary artery bypass graft CABG surgery using cardiopulmonary bypass CPB. This study aims to understand whether giving these patients carbohydrate drinks before surgery can reduce insulin resistance and improve clinical outcomes like infection rates and ICU stay length. The research also looks at inflammatory markers such as CRP levels to better understand physiological changes. Participants are randomly assigned to one of two groups. One group will receive carbohydrate loading 2 hours before surgery, consisting of 400 ml of 12.5% maltodextrin and 400 ml of fruit-based lemonade. The other group will follow the traditional fasting protocol, avoiding food and drink for 8 hours before surgery. This randomized controlled trial compares these two approaches to assess their impact on surgery outcomes. During the study, patients will have tests like the Short Insulin Tolerance Test KITT before surgery and up to 72 hours afterward to monitor insulin resistance. Additional assessments include measuring CRP levels, arterial blood gases, operative time, cardiopulmonary bypass duration, blood loss, number of grafts performed, use of inotropic drugs, and any complications. These evaluations help researchers understand the clinical and physiological effects of carbohydrate loading during the surgical period.

Efficacy of Carbohydrate Loading in Diabetic Type 2 Patients Undergoing CABG Surgery on CPB