Associations Between Dietary Intake and Cardiometabolic and Gut Microbiota Outcomes in Singapore Adults

What this Trial Is About

This research aims to explore the connections between dietary intake, markers of cardiometabolic health, and gut microbiota composition in adults living in Singapore. It addresses the lack of studies focusing on Asian populations by considering their unique genetic, metabolic, and dietary characteristics. The goal is to better understand how diet influences health outcomes specific to this population and to contribute to improved dietary guidelines. The study is observational and cross-sectional, involving adults aged 21 to 80 years. Participants are grouped by age into younger (21-64 years) and middle-aged to older adults (65-80 years). Researchers collect detailed dietary information over seven days and measure various health markers, including blood pressure, blood lipids, fasting glucose, endothelial progenitor cell counts, and several fecal biomarkers related to gut health. Additional assessments cover sleep quality, cognitive function, skin carotenoid levels, physical activity, stress, anxiety, depression, vision, and advanced skin glycation end products. Participants will attend a study visit where blood and fecal samples are collected alongside completing questionnaires and physical assessments. Researchers evaluate primary outcomes such as dietary intake and multiple health biomarkers on the first day, while secondary outcomes include sleep, mental health, physical activity, and vision measures. The study provides valuable insights into diet’s impact on cardiometabolic and gut health and lasts from the start visit until all assessments are completed, with no treatment administered.

Associations Between Dietary Intake and Cardiometabolic and Gut Microbiota Outcomes