Studying Platelet-Rich Plasma Injections to Improve Tear Production in Severe Dry Eye Syndrome

What this Trial Is About

Researchers are evaluating the effectiveness of Platelet-Rich Plasma PRP injections into the lacrimal gland to help restore tear production in patients with severe dry eye syndrome caused by aqueous deficiency. The study focuses on patients diagnosed with severe dry keratoconjunctivitis, aiming to assess how PRP may improve lacrimal secretion and relieve symptoms associated with dry eyes. Participants will receive four injections of PRP directly into the lacrimal gland, administered once a month during the study period. This approach is being studied to determine whether repeated PRP injections can enhance tear production and improve clinical signs of dry eye syndrome. During the study, researchers will monitor lacrimal secretion levels and various clinical parameters related to both the quality and quantity of tears after the four monthly PRP injections. The primary outcome is to compare tear production at week 16, with additional follow-up assessments to evaluate the overall improvement in dry eye symptoms. Participants will be observed throughout the study to track these outcomes and ensure safety.

Efficacy of Platelet-Rich Plasma Injection in Dry Eye Syndrome