Evidence-based palliative care in the intensive care unit: a systematic review of interventions.
Rebecca Aslakson, Jennifer Cheng, Daniela Vollenweider...
https://pubmed.ncbi.nlm.nih.gov/24517300Actively Recruiting
Led by Washington University School of Medicine · Updated on 2025-07-16
2600
Participants Needed
1
Research Sites
52 weeks
Total Duration
This research aims to assess whether placing a hospice and palliative care practitioner directly inside a medical intensive care unit (ICU) improves patient outcomes, use of palliative and hospice care, and overall healthcare quality. The study focuses on medically complex patients admitted to two nearby medical ICUs at a large referral center. Currently, palliative care is provided only when requested by ICU clinicians, often late in the patient's stay, which can delay needed support and hospice transfers. The study compares three groups: patients in an ICU with the embedded practitioner who proactively offers timely palliative care consultations based on clinical criteria and mortality risk; patients in a second ICU where the practitioner is not embedded but available for standard consultations; and historical patients treated before the study began. Initially, the practitioner works in one ICU and later expands to both units to provide early and on-demand palliative and hospice consultations. Participants will be admitted to one of the medical ICUs during the study period. Researchers will track many outcomes including ICU and hospital length of stay, code status changes, advance care planning documentation, hospice and palliative care consultations and enrollment, mortality, readmissions, and healthcare costs up to one year after enrollment. These measures will help determine if embedding the practitioner improves care quality and patient experiences in the ICU setting.
CONDITIONS
Embedded Palliative Care in the MICU
You may qualify if you...
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Duration of ICU stay until hospital discharge
Participants receive care in a medical intensive care unit where a palliative care and hospice practitioner is embedded to provide early and proactive palliative care consultations, as well as standard hospice and palliative care consultations as needed.
Continuous care during ICU stay
Duration - Up to 1 year after hospital discharge
Participants are monitored for up to one year after hospital discharge for outcomes related to code status, advance care planning, hospice enrollment, hospital readmissions, and mortality.
Assessments at 30 days and periodic follow-up visits as needed
Total: 1 location
1
Barnes Jewish Hospital
St Louis, Missouri, United States, 63110
Actively Recruiting
S
Stephen Chi, MD
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
3
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