Actively Recruiting
Large Polyp Study III: Observational Cohort on Endoscopic Resection of Large Colorectal and Duodenal Polyps
Led by White River Junction Veterans Affairs Medical Center · Updated on 2024-07-05
1500
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying how to safely and effectively remove large colorectal and duodenal polyps to help prevent colorectal and duodenal cancers. This observational cohort study builds on previous trials and aims to understand outcomes in a broader patient group, including those who might not have qualified for prior trials. The study also seeks to verify whether findings from earlier research apply to different populations and to explore evolving endoscopic resection techniques. The study observes patients undergoing endoscopic removal of large polyps, specifically colon polyps 20 mm or larger and duodenal polyps 10 mm or larger. It complements ongoing randomized trials by including patients and resection methods not covered in those studies. The research tracks outcomes such as complication rates and polyp recurrence over time, without assigning specific treatments. Participants will be monitored for complications within 14 days after the procedure, with polyp removal completeness evaluated during the procedure. Long-term follow-up includes surveillance colonoscopies up to five years later to check for polyp recurrence. Additional assessments cover bleeding, perforation, and technical aspects of the procedure. The total participation duration varies based on surveillance schedules, and the study records safety and efficacy data throughout this period.
CONDITIONS
Brief Title
Endoscopic Resection of Large Colorectal Polyps: An Observational Cohort Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Any patient 18 years or older presenting for an upper endoscopy or colonoscopy
- Patients with a colon polyp 20 mm or larger
- Patients with a duodenal polyp 10 mm or larger
You will not qualify if you...
- Patients undergoing emergency endoscopy
- Patients with coagulopathy, including INR of 1.5 or higher or platelet count below 50
- Patients with poor bowel preparation
- Pregnant patients
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 1 day
Participants undergo an endoscopic procedure to remove large colorectal or duodenal polyps and assess the completeness of polyp resection.
1 visit (in-person)
Duration - Up to 5 years
Participants are monitored for complications and polyp recurrence after the procedure.
Scheduled surveillance colonoscopy visits as recommended
Trial Site Locations
Total: 1 location
1
White River Junction VAMC
White River Junction, Vermont, United States, 05009
Actively Recruiting
Research Team
H
Heiko Pohl, MD
L
Laura L Jensen, MPH
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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