Actively Recruiting

Phase Not Applicable
Age: 18Years - 83Years
All Genders
NCT06586164

Enhancing Rehabilitation for Veterans With Serious Mental Illness

Led by VA Office of Research and Development · Updated on 2026-01-30

80

Participants Needed

1

Research Sites

192 weeks

Total Duration

On this page

Sponsors

V

VA Office of Research and Development

Lead Sponsor

U

University of California, San Diego

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study addresses the critical need for innovative therapeutic interventions in Veterans with serious mental illnesses (SMI) receiving care in VA Psychosocial Rehabilitation and Recovery Centers (PRRCs). The vast majority of individuals with SMI suffer from cognitive impairments, leading to chronic functional disability, and impaired outcomes, causing a significant strain on support networks and the VA healthcare system. This study aims to introduce an innovative mental health therapy, Targeted Cognitive Training (TCT), to Veterans struggling with serious mental illnesses (SMI). TCT works to improve basic sensory information processing and, ultimately, clinical, cognitive, and psychosocial functioning. By using EEG biomarkers to identify Veterans with SMI receiving care within VA Psychosocial Rehabilitation and Recovery Centers who are most likely to benefit from this treatment, and by understanding how best to implement this therapy, the investigators hope to enhance care and improve life quality for Veterans with SMI.

CONDITIONS

Official Title

Enhancing Rehabilitation for Veterans With Serious Mental Illness

Who Can Participate

Age: 18Years - 83Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Veterans with serious mental illness (such as schizophrenia, schizoaffective disorder, bipolar disorder, or PTSD) receiving treatment at VA Psychosocial Rehabilitation and Recovery Centers or similar services
  • Age between 18 and 83 years
  • Fluency in spoken and written English
  • Ability to hear a 1000 Hz tone at 40 decibels in both ears
  • Visual acuity of 20/40 or better in both eyes together, corrected if needed
Not Eligible

You will not qualify if you...

  • Estimated premorbid IQ below 70 based on reading test
  • Active substance use other than cannabis within the last 30 days
  • History of significant medical or neurological illness
  • Unable to understand or give informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

VA San Diego Healthcare System, San Diego, CA

San Diego, California, United States, 92161-0002

Actively Recruiting

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Research Team

J

Joyce Sprock, BS

CONTACT

A

Abigail A Mack

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Enhancing Rehabilitation for Veterans With Serious Mental Illness | DecenTrialz