Actively Recruiting

Phase Not Applicable
Age: 7Years +
All Genders
Healthy Volunteers
NCT06236100

Evaluating an Adverse Childhood Experience-Targeting Advocate Model of a Substance Use Prevention Program

Led by RTI International · Updated on 2026-05-05

360

Participants Needed

1

Research Sites

200 weeks

Total Duration

On this page

Sponsors

R

RTI International

Lead Sponsor

N

New Jersey Prevention Network

Collaborating Sponsor

AI-Summary

What this Trial Is About

Primary Objective: Conduct a rigorous evaluation of a prevention-based intervention designed to mitigate the harms of adverse childhood experiences (ACEs) exposure and prevent future ACEs, substance use, and overdose within 36 communities experiencing a disproportionate burden of substance use and ACEs. The study has three aims: (1) use a cluster randomized controlled trial to test effectiveness of the Strengthening Families Program (SFP) + Family Advocate (FA) intervention on substance use, overdose, and ACEs in 18 communities compared with SFP-only in 18 communities; (2) conduct a robust process evaluation informed by the Consolidated Framework for Implementation Research (CFIR) to explore implementation barriers and facilitators; and (3) conduct a cost evaluation to accurately estimate the costs required to implement SFP and SFP+FA and assess the cost-effectiveness of SFP+FA relative to SFP alone. Findings will provide a roadmap about the best ways to help disproportionately affected communities prevent substance use, overdose, and ACEs.

CONDITIONS

Official Title

Evaluating an Adverse Childhood Experience-Targeting Advocate Model of a Substance Use Prevention Program

Who Can Participate

Age: 7Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Reside in or attend SFP meetings in one of the 36 New Jersey communities with high levels of ACEs and substance use
  • Have one or more adult caregivers in the family
  • Have one or more adolescents aged 7 to 17
  • Caregiver provides signed and dated informed consent
  • Children provide informed assent and parental permission
  • Willingness to follow all study procedures and be available for the study duration
  • Willingness to participate in the SFP and Family Advocate interventions
  • Access to technology needed for participation (computer, smartphone, internet)
Not Eligible

You will not qualify if you...

  • Caregiver has previously completed the Strengthening Families Program with one or more children aged 7 to 17
  • Intellectual disabilities that prevent completing the program or data collection
  • Caregivers and children unable to read and understand spoken English

AI-Screening

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Trial Site Locations

Total: 1 location

1

New Jersey Prevention Network

Tinton Falls, New Jersey, United States, 07724

Actively Recruiting

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Research Team

A

Andrea L. Zapcic, BA

CONTACT

B

Brittany Simon, MA

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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