Actively Recruiting
Evaluation of the Effect of Pulmonary Rehabilitation on Patients With High Flow Oxygen Therapy
Led by Chinese PLA General Hospital · Updated on 2026-02-09
70
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the effect of pulmonary rehabilitation on patients in the intensive care unit (ICU) who are receiving high flow humidified oxygen therapy. This study aims to compare pulmonary rehabilitation with routine medical treatment to understand its impact on lung function and overall recovery in patients with pulmonary disease. The trial is randomized and double-blinded, involving patients aged 18 to 100 years with stable hemodynamics and respiratory status. Participants are randomly assigned to one of two groups: one group receives pulmonary rehabilitation therapy, which includes personalized exercise training, education, and behavioral changes to improve physiological and psychological health. The other group receives routine medical treatment without rehabilitation. The study period lasts 28 days, during which patients are closely monitored and assessed. Throughout the study, patients undergo various evaluations including bedside diaphragm ultrasound, muscle strength tests, sitting tests, and assessments of dyspnea and daily functioning. Vital signs are monitored daily, and arterial blood gas analyses are performed at admission and discharge. Researchers also track the use of non-invasive ventilation, intubation rates, complications, and time to first mobilization. The primary outcomes focus on muscle strength, diaphragm function, and oxygenation measurements at day 28, with additional follow-up on ICU stay, hospitalization time, and mortality up to three months.
CONDITIONS
Brief Title
Evaluation of the Effect of Pulmonary Rehabilitation on Patients With High Flow Oxygen Therapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Stable hemodynamics
- Heart rate between 50 and 120 beats per minute
- Systolic blood pressure between 90 and 200 mmHg
- Mean arterial pressure between 55 and 120 mmHg
- No increase in pressor drug dose for at least 2 hours
- Stable intracranial pressure with no seizures in past 24 hours
- Stable respiratory status
- Finger pulse oxygen saturation of 88% or higher
- Respiratory rate between 10 and 35 breaths per minute
You will not qualify if you...
- Pregnancy
- Acute cardio-cerebrovascular events
- Spinal or limb fractures
- Active bleeding
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Up to 28 days
Participants receive pulmonary rehabilitation therapy or routine medical treatment while in the ICU using high flow humidification apparatus. Daily vital sign monitoring and bedside diaphragm ultrasound assessments are performed.
Daily assessments during ICU stay
Trial Site Locations
Total: 1 location
1
Chinese PLAGH Hospital
Beijing, Beijing Municipality, China
Actively Recruiting
Research Team
K
kai fei Wang
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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