Actively Recruiting
Evaluation and Further Development of an Artificial Intelligence-based Algorithm for Clinical Decision Support in Invasive Mechanical Ventilation of Intensive Care Patients
Led by Technische Universität Dresden · Updated on 2026-04-21
318542
Participants Needed
8
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to evaluate and improve an artificial intelligence (AI) algorithm designed to support clinical decisions in invasive mechanical ventilation for intensive care patients. Mechanical ventilation is a life-saving therapy in the ICU but can cause organ damage if settings are not properly adjusted. The study focuses on learning from how healthcare providers adjust ventilator and extracorporeal lung support device settings to reduce risks and enhance patient care. The study uses retrospective patient treatment data to assess an AI-based decision support system called IntelliLung. This system helps optimize mechanical ventilation settings by analyzing both the AI recommendations and the actual clinical decisions made by experts. The research compares the time when the AI settings match the healthcare provider's settings from intubation until extubation or discharge, with assessment up to 12 months. Participants are ICU patients aged 18 or older who have received invasive mechanical ventilation for more than 4 hours. The study involves reviewing ventilator settings and patient data during their ICU stay. Researchers measure how often the AI's recommended settings align with those chosen by clinicians. This observational study does not involve active treatment changes but focuses on the analysis of existing patient data to improve future ventilation support.
CONDITIONS
Brief Title
Evaluation and Further Development of an Artificial Intelligence-based Algorithm for Clinical Decision Support
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Subjects who are 18 years or older and receive invasive mechanical ventilation for > 4 hours
You will not qualify if you...
- Patients receiving one-lung ventilation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - From date of intubation to date of extubation or discharge, up to 12 months
Participants who receive invasive mechanical ventilation are observed while the Artificial Intelligence-based Decision support optimizes ventilation settings.
Continuous monitoring during ventilation period
Trial Site Locations
Total: 8 locations
1
Cleveland Clinic Foundation, Cleveland, USA
Cleveland, Ohio, United States, 44195
Actively Recruiting
2
University Hospital Carl Gustav Carus Dresden
Dresden, Germany
Actively Recruiting
3
Institut Fur Angewandte Informatik (Infai) Ev
Leipzig, Germany
Active, Not Recruiting
4
Institut Mihajlo Pupin
Belgrade, Serbia
Active, Not Recruiting
5
Better Care Sl
Sabadell, Spain
Active, Not Recruiting
6
Fundacio Parc Tauli
Sabadell, Spain
Completed
7
Fundacion Publica Andaluza Progreso Y Salud
Seville, Spain
Active, Not Recruiting
8
Inselspital, Universitätsspital Bern
Bern, Switzerland
Completed
Research Team
J
Jakob Wittenstein, MD
T
Thea Koch, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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