Actively Recruiting
Evaluation of Gas Humidification Practices in Patients Under Invasive Mechanical Ventilation: Benefit of the F & P950 Heated Humidifier Compared With the MR 850 on Clinical Events of Under-humidification
Led by Laval University · Updated on 2025-08-28
40
Participants Needed
1
Research Sites
30 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the use of two different heated humidifiers for patients who require invasive mechanical ventilation in intensive care. The study aims to compare the effectiveness and clinical outcomes of the Fisher & Paykel MR850 and FP950 humidifiers. Mechanical ventilation requires proper humidification to manage respiratory secretions and prevent complications, and this study focuses on assessing these humidification methods based on data collected retrospectively starting from June 2021. The study involves two groups of patients, each using one of the two heated humidifiers (MR850 or FP950) during their mechanical ventilation period, which is expected to last longer than 24 hours. Both humidifiers are already in use in ICU settings, and the study will observe their impact on clinical events related to insufficient humidification. The comparison focuses on practical application and performance in real clinical scenarios. Participants are monitored for events such as endotracheal tube occlusion requiring emergency tube change, bronchoscopy, tracheal saline instillations, presence of thick secretions, and changes in humidifier settings during the mechanical ventilation period or up to 21 days. Data collection is retrospective, and the study will also look at other factors potentially affected by humidification quality. This research is sponsored by Laval University and will continue until July 2026.
CONDITIONS
Brief Title
Evaluation of Gas Humidification Practices in Patients Under Invasive Mechanical Ventilation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years old or older
- Admitted to intensive care
- Under invasive mechanical ventilation with usual indications for a heated humidifier (prolonged ventilation or protective ventilation needing high respiratory rates)
You will not qualify if you...
- Mechanical ventilation immediately after surgery for less than 24 hours
- Imminent extubation or planned intubation expected to last less than 24 hours
- Enrolled in the SAVE-ICU study group receiving volatile agents with the AnaConDa system
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Up to 21 days or until the end of mechanical ventilation, whichever occurs first.
Participants receive one of two types of heated humidifiers during invasive mechanical ventilation as part of routine care.
Continuous monitoring during mechanical ventilation period
Trial Site Locations
Total: 1 location
1
Institut Universitaire de Cardiologie et de Pneumologie de Québec
Québec, Quebec, Canada, G1V4G5
Actively Recruiting
Research Team
F
François Lellouche
P
Pierre-Alexandre Bouchard
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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