The National Marrow Donor Program.
D Stroncek, G Bartsch, H A Perkins...
https://pubmed.ncbi.nlm.nih.gov/8333020Completed
Age: 18Years - 60Years
All Genders
Healthy Volunteers
ID00001451
Evaluation of Healthy Volunteer Marrow Donors Participating in the National Marrow Donor Program (NMDP)
Led by National Institutes of Health Clinical Center (CC) · Updated on 2017-07-02
57
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Individuals interested in becoming prospective bone marrow donors and joining the Registry of the National Marrow Donor Program (NMDP) should do so by calling 301-496-0572, the phone number of the NIH Marrow Donor Center. An appointment will be made to have a health history taken and to have a buccal swab collected for tissue (HLA) typing. The current protocol only involves donors already registered with the NMDP, who have been identified as "perfect matches" for an unrelated patient requiring a bone marrow transplant, and who require expedited medical evaluation prior to marrow collection.
CONDITIONS
Official Title
Evaluation of Healthy Volunteer Marrow Donors Participating in the National Marrow Donor Program (NMDP)
Who Can Participate
Age: 18Years - 60Years
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- INCLUSION CRITERIA:
Age 18-60.
Must meet same criteria as that of a volunteer blood donor.
EXCLUSION CRITERIA:
History of hepatitis.
History of intravenous use of illicit drugs.
History of activities that increase the risk of exposure to HIV or hepatitis viruses.
Confirmed positive test for HIV
Inability to tolerate general anesthesia.
Obesity.
Hypertension.
Asthma.
Diabetic patients will be excluded.
Pregnant patients will be excluded.
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Trial Site Locations
Total: 1 location
1
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892
Status Unknown
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How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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Published Research Related To This Trial
Analysis of 462 transplantations from unrelated donors facilitated by the National Marrow Donor Program.
N A Kernan, G Bartsch, R C Ash...
https://pubmed.ncbi.nlm.nih.gov/8429851Quinine-dependent antibodies to neutrophils react with a 60-Kd glycoprotein on which neutrophil-specific antigen NB1 is located and an 85-Kd glycosyl-phosphatidylinositol-linked N-glycosylated plasma membrane glycoprotein.
D F Stroncek, R A Shankar, G P Herr
https://pubmed.ncbi.nlm.nih.gov/8387837