Actively Recruiting

Phase Not Applicable
Age: 0 - 17Years
All Genders
ID06771830

A Rapid Diagnostic of Risk in Hospitalized Pediatric Patients to Improve Outcomes Using Machine Learning

Led by University of Wisconsin, Madison · Updated on 2025-12-17

30000

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

U

University of Wisconsin, Madison

Lead Sponsor

A

AgileMD, Inc.

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating the implementation of a pediatric version of the Electronic Cardiac Arrest Risk Triage (pediatric eCART) tool. This clinical decision support system uses electronic health records to identify children at high risk for life-threatening outcomes, aiming to improve clinical decision-making and patient management. The study compares three years of retrospective data before pediatric eCART implementation to two years of prospective data after its adoption at UW Health. Additionally, the study measures nurse clinicians' acceptance of the tool to understand its usability and impact on their workload. The intervention involves integrating pediatric eCART into the electronic health record system Epic, allowing real-time scoring of hospitalized children under 18 years old. The "pre" group includes patients admitted between January 2022 and the 2025 implementation date, with retrospective scoring applied. The "post" group consists of patients admitted during the two years following implementation (2025-2027), with scores calculated live. Pediatric nurse clinicians using the system will also be surveyed to assess the tool's acceptability and usability. Participants include hospitalized pediatric patients and UW Health nurses who interact with the pediatric eCART during care. The study will track outcomes such as in-hospital mortality and intensive care unit (ICU) free days during hospital stays, typically around 5 days but possibly longer. Nurses will complete surveys assessing system usability and perceived usefulness within a month of using pediatric eCART. The total study period spans from the retrospective data collection through two years of prospective monitoring after implementation.

CONDITIONS

Brief Title

Evaluation of Pediatric eCART Implementation

Who Can Participate

Age: 0 - 17Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • All pediatric patients scored on pediatric eCART or eligible for scoring on either algorithm in the pre-implementation period will be screened for study eligibility
  • Patients eligible for pediatric eCART scoring include pediatric patients under 18 years of age
  • Patients must be in inpatient locations
  • UW Health nurses who interact with pediatric eCART during patient care
Not Eligible

You will not qualify if you...

  • Patients who are ineligible for pediatric eCART scoring
  • Neonates and birth encounters are excluded from the pediatric eCART study
  • UW Health nurses no longer employed at UW Health

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Implementation

Duration - Up to 2 years following implementation

Participants are monitored with the pediatric eCART clinical decision support tool integrated into the electronic health record to assess risk of critical illness.

Continuous monitoring during hospital stay (typically up to 5 days, but may be over 60 days)

Post-Hospitalization Follow-up

Duration - Up to 1 month

Nurses complete surveys on the usability and acceptability of the pediatric eCART tool within a month after using the interface.

Surveys automatically sent within a week of interface use

Trial Site Locations

Total: 1 location

1

American Family Children's Hospital

Madison, Wisconsin, United States, 53792

Actively Recruiting

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Research Team

A

Anoop Mayampurath, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

1

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