PANTHERA Study: Pelvic Floor Disorders in Patients Under Antineoplastic Therapy

What this Trial Is About

This research focuses on patients with gynecological cancers and breast cancer who are undergoing systemic tumor therapy. It aims to study how these treatments might affect the function of the pelvic floor, including bladder, bowel, and sexual function, since such impairments can significantly reduce quality of life. The study will use validated disease-specific questionnaires to understand patients' subjective experiences and identify factors that influence these symptoms. Participants will be monitored during their cancer treatment without any additional interventions or experimental therapies, as this is an observational study. The study collects information through questionnaires designed to assess pelvic floor function and related symptoms. The goal is to find potential ways to prevent or treat these issues in cancer patients receiving systemic therapy. Throughout the study, participants will complete questionnaires at various points to report on their pelvic floor function. Researchers will evaluate primary and secondary outcomes at 12 months to analyze changes over time. This approach allows for careful monitoring of symptoms without altering standard cancer treatment, and the study will continue until the end date in 2026.

Evaluation of the Subjectively Perceived Pelvic Floor Function in Patients With Gynecological Tumors and Breast Cancer Under Systemic Tumor Therapy Using a Validated Questionnaire