Actively Recruiting

Phase Not Applicable
Age: 18Years - 35Years
All Genders
Healthy Volunteers
NCT04916327

Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 1

Led by Virginia Commonwealth University · Updated on 2026-05-05

720

Participants Needed

1

Research Sites

244 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this research study is to examine the role oxidants, substances produced in the blood that can damage blood vessel function, may play in blood vessel function in healthy individuals as well as individuals with mental health disorders (posttraumatic stress disorder (PTSD) and/or generalized anxiety disorder (GAD)).

CONDITIONS

Official Title

Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 1

Who Can Participate

Age: 18Years - 35Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Apparently healthy without cardiovascular, lung, or metabolic diseases
  • For PTSD group, a score of 33 or higher on the PCL-5 checklist
  • For GAD group, a score of 10 or higher on the GAD-7 scale and less than 33 on the PCL-5 checklist
  • For Healthy Control group, a score of 10 or lower on the GAD-7 scale and less than 33 on the PCL-5 checklist
Not Eligible

You will not qualify if you...

  • Taking medications that may affect cardiovascular function
  • Current smokers or those who recently quit smoking
  • Illicit drug use or excessive alcohol drinking
  • Pregnant women
  • Significant calorie restriction or vitamin/mineral deficiencies
  • Limited English proficiency

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Virginia Commonwealth University

Richmond, Virginia, United States, 23298

Actively Recruiting

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Research Team

R

Ryan Garten, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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