Actively Recruiting
Exercise-Induced Hypoalgesia Differences at Proximal and Distal Regions After Lower or Upper Limb Resistance Training: A Randomized Controlled Trial in Healthy Adults
Led by Centro Universitario La Salle · Updated on 2025-02-26
90
Participants Needed
1
Research Sites
1 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying how exercise-induced hypoalgesia, which is a reduced sensitivity to pain after exercise, differs when resistance training is applied to the lower limbs compared to the upper limbs. This randomized controlled trial involves healthy adults aged 18 to 64 years and aims to compare pain pressure thresholds in specific muscle groups after different exercise interventions. The study also includes a control group to observe differences without exercise intervention. Participants are divided into three groups: one group performs lower limb resistance training using leg extensions, another performs upper limb resistance training with brachial biceps curls, and a control group remains seated without exercise. Both exercise groups complete 3 sets of 5 repetitions at a resistance level determined by their 5-repetition maximum (5RM), following a 5-minute warm-up on a cycle ergometer. The 5RM is assessed 72 hours before the intervention. During the study, pain pressure thresholds on the dominant quadriceps and brachial biceps are measured before, immediately after, and 30 minutes after the exercise or rest period. Participants also complete questionnaires assessing physical activity, fatigue, and perceived exertion. The research aims to observe local and distant pain sensitivity changes based on the area of resistance training, with all testing conducted under controlled conditions.
CONDITIONS
Brief Title
Exercise-Induced Hypoalgesia Differences Between Upper and Lower Limbs Resistance Training Interventions
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Asymptomatic subjects aged between 18 and 64 years.
You will not qualify if you...
- Cardiovascular, respiratory, metabolic, neurological, or osteomuscular signs or pathologies.
- History of epilepsy.
- Pregnant.
- Participants with any pain on the day of measurements or frequent pain in the previous 12 weeks.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Single session
Participants undergo either lower limb or upper limb resistance training, or remain seated if in the control group. Lower limb training involves leg extensions with specific resistance exercises after a warm-up. Upper limb training involves brachial biceps curls with similar resistance exercises after a warm-up. Control participants remain seated without intervention.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
CSEU LaSalle
Madrid, Spain, 28023
Actively Recruiting
Research Team
Á
Álvaro Reina-Varona, MSc
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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