Actively Recruiting

Phase Not Applicable
Age: 18Years - 64Years
All Genders
Healthy Volunteers
ID06765486

Exercise-Induced Hypoalgesia Differences at Proximal and Distal Regions After Lower or Upper Limb Resistance Training: A Randomized Controlled Trial in Healthy Adults

Led by Centro Universitario La Salle · Updated on 2025-02-26

90

Participants Needed

1

Research Sites

1 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying how exercise-induced hypoalgesia, which is a reduced sensitivity to pain after exercise, differs when resistance training is applied to the lower limbs compared to the upper limbs. This randomized controlled trial involves healthy adults aged 18 to 64 years and aims to compare pain pressure thresholds in specific muscle groups after different exercise interventions. The study also includes a control group to observe differences without exercise intervention. Participants are divided into three groups: one group performs lower limb resistance training using leg extensions, another performs upper limb resistance training with brachial biceps curls, and a control group remains seated without exercise. Both exercise groups complete 3 sets of 5 repetitions at a resistance level determined by their 5-repetition maximum (5RM), following a 5-minute warm-up on a cycle ergometer. The 5RM is assessed 72 hours before the intervention. During the study, pain pressure thresholds on the dominant quadriceps and brachial biceps are measured before, immediately after, and 30 minutes after the exercise or rest period. Participants also complete questionnaires assessing physical activity, fatigue, and perceived exertion. The research aims to observe local and distant pain sensitivity changes based on the area of resistance training, with all testing conducted under controlled conditions.

CONDITIONS

Brief Title

Exercise-Induced Hypoalgesia Differences Between Upper and Lower Limbs Resistance Training Interventions

Who Can Participate

Age: 18Years - 64Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Asymptomatic subjects aged between 18 and 64 years.
Not Eligible

You will not qualify if you...

  • Cardiovascular, respiratory, metabolic, neurological, or osteomuscular signs or pathologies.
  • History of epilepsy.
  • Pregnant.
  • Participants with any pain on the day of measurements or frequent pain in the previous 12 weeks.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Single session

Participants undergo either lower limb or upper limb resistance training, or remain seated if in the control group. Lower limb training involves leg extensions with specific resistance exercises after a warm-up. Upper limb training involves brachial biceps curls with similar resistance exercises after a warm-up. Control participants remain seated without intervention.

1 visit (in-person)

Trial Site Locations

Total: 1 location

1

CSEU LaSalle

Madrid, Spain, 28023

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Research Team

Á

Álvaro Reina-Varona, MSc

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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