Study of Exparel Injection to Manage Pain After Adult Tonsillectomy Surgery

What this Trial Is About

Tonsillectomy is a common surgical procedure in adults, often performed for recurrent throat infections and obstructive issues. This trial evaluates the use of a long-acting local anesthetic called bupivacaine liposome injectable suspension Exparel to help manage pain after tonsillectomy. The study aims to see if adding Exparel to the standard pain control medication can reduce pain intensity and the need for other pain medicines during the critical first days after surgery. Participants are randomly assigned to receive either the standard care medication, bupivacaine HCl with epinephrine, or the standard care followed by the adjunct Exparel. Both treatments are given by injection into specific areas around the tonsil location immediately after tonsil removal and before waking from anesthesia. This approach is designed to directly target the surgical site to control pain. During the study, participants pain levels are monitored at several points after surgery, specifically on days 1, 2, 3, 5, and 10. Researchers also track how much prescribed narcotic and over-the-counter pain medication participants use during this time. The goal is to assess changes in pain and medication needs. The study involves a single treatment administration during surgery and follow-up observations over 10 days to evaluate outcomes and recovery.

EXPAREL Post-tonsillectomy Clinical Trial