Long-Term Study of Amygdalo-Hippocampectomy Using Prof. Coubes Surgical Technique for Hippocampal Sclerosis and Other Temporal Diseases

What this Trial Is About

This research aims to evaluate the long-term outcomes and complications of amygdalo-hippocampectomy using the surgical method developed by Professor Coubes at the University Hospital of Montpellier. It focuses on patients treated for hippocampal sclerosis and other internal temporal diseases, investigating factors associated with better seizure control and the evolution of clinical results. The study includes data from 234 patients treated over the past 30 years, covering both adults and children. The study analyzes clinical information retrospectively, including demographics, surgical and imaging data, and seizure outcomes based on ILAE criteria. It examines post-operative complications, return-to-work rates, and social reintegration. The method studied features precise anatomical targeting and surgical pathways designed to reduce neurological deficits and improve seizure control, distinguishing it from other surgical techniques such as the Yasargil approach. Participants medical records will be reviewed to collect data on seizure control, complications like infections and hematomas, and medication use before and after surgery. Statistical analyses will identify predictors of success or failure after surgery. The study spans from 2024 to 2025 and ensures data privacy by pseudonymizing patient information. Results aim to provide clinical insights, comparative perspectives, and educational value in neurosurgical practice.

Exploration and Evaluation of Amygdalo-Hippocampectomy According to Prof. Coubes' Technique: An Anatomical, Clinical, and Educational Approach