Sonography-guided Resection of Brain Mass Lesions: a Prospective, Single Arm Clinical Trial

What this Trial Is About

This research aims to explore the use of intraoperative sonography for detecting and assessing brain mass lesions such as tumors, vascular malformations, cavernomas, and hematomas during surgery. Sonography is used to observe brain tissue in real time, offering a cheaper and workflow-friendly option compared to traditional imaging, though it has challenges like a learning curve and lower image quality than MRI. The study seeks to define when ultrasound-guided needles or wire-guided ports are helpful for reaching deep or small lesions. During surgery, the surgeon will use ultrasound through the surgical opening to locate the brain mass and evaluate how much has been removed. Scanning may be done periodically or continuously through the same or an expanded opening. The study also involves using ultrasound-guided tools to assist in accessing deeper brain areas. This is a single-arm clinical trial assessing ultrasound-guided resection of various brain lesions. Participants will be evaluated with ultrasound during surgery and undergo imaging tests like MRI or CT before and after surgery to compare findings. Researchers will measure ultrasound features of lesions, accuracy in detecting residual masses, surgery durations, and patient recovery status. Monitoring includes cerebral complications from ICU admission until hospital discharge, lasting up to one year. The trial spans from initial surgery through post-operative assessments within days and long-term follow-up for safety.

Sonography-guided Resection of Brain Mass Lesions