Actively Recruiting

Age: 18Years - 85Years
All Genders
Healthy Volunteers
NCT06171659

FDG PET/MR Imaging of Peripheral Pain Generators

Led by University of Wisconsin, Madison · Updated on 2025-09-25

128

Participants Needed

1

Research Sites

132 weeks

Total Duration

On this page

Sponsors

U

University of Wisconsin, Madison

Lead Sponsor

N

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this research is to determine if a PET/MRI scan using FDG can accurately identify the source of chronic pain. Identifying the source of pain may help doctors treat chronic pain more effectively. Approximately 128 participants will be enrolled and can expect to be on study for up to 12 months.

CONDITIONS

Official Title

FDG PET/MR Imaging of Peripheral Pain Generators

Who Can Participate

Age: 18Years - 85Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 to 85 years old
  • Persistent pain with a score of 4 or higher on a 0 to 10 scale for at least 6 months after joint arthroplasty or arthroscopy
  • Able and willing to provide informed consent
  • Willing and able to undergo PET/MRI (all participants) and PET/CT imaging (arthroplasty participants only)
  • For healthy controls: 18 to 85 years old and asymptomatic with pain score of 2 or lower for at least 6 months after joint arthroplasty or arthroscopy
Not Eligible

You will not qualify if you...

  • Unable to understand or communicate to complete study questionnaires
  • Severe systemic disease limiting function (ASA physical status classification greater than 3) such as recent or current pulmonary, liver, kidney, arthritis, blood, or neurological diseases not related to chronic pain
  • Pregnant or breastfeeding
  • Contraindications to or inability to undergo PET/MRI
  • Current diagnosis of any cancer (except remission for at least two years without treatment per investigator discretion)
  • Currently enrolled in another interventional or treatment study
  • Unable or unwilling to provide informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

UW School of Medicine and Public Health

Madison, Wisconsin, United States, 53792

Actively Recruiting

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Research Team

R

Radiology Studies

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

4

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