Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID07247617

Semi-rigid Ureteroscopy Versus Flexible Ureteroscopy in Upper Third Ureteric Stones Management: a Prospective Randomized Trial

Led by Assiut University · Updated on 2025-11-25

100

Participants Needed

1

Research Sites

13 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the effectiveness, safety, success rates, operation times, and cost differences between flexible ureteroscopy and semirigid ureteroscopy for treating upper ureteric stones smaller than 2 cm. The study focuses on determining which patients with upper third ureteric stones can be treated with semirigid ureteroscopy and which require flexible ureteroscopy, considering factors such as stone size, stone impaction, ureter anatomy, surgeon experience, anesthesia, and ureteric dilation. Participants receive either flexible ureteroscopy or semirigid ureteroscopy, both minimally invasive procedures to remove stones from the upper ureter. Flexible ureteroscopy allows more maneuverability and access to difficult stone locations, while semirigid ureteroscopy is typically faster and less costly but may be less effective for complex cases. Both use holmium laser lithotripsy to break the stones. Treatment choice depends on stone location, size, surgeon preference, and equipment availability. During the study, participants will be monitored for stone-free status at 3 months post-procedure, along with assessments of safety, operation time, and cost-effectiveness. Researchers will track operative success and complications to compare outcomes between the two methods. The study involves regular follow-ups to evaluate treatment success and ensure patient safety throughout the trial period.

CONDITIONS

Brief Title

Flexible vs Semi-rigid URS

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients 18 years or older
  • Upper ureteric stone
  • Stone size 20 mm or smaller
Not Eligible

You will not qualify if you...

  • Associated renal stones
  • Any contraindications to anesthesia

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Treatment

Duration - Single procedure with follow-up over 3 months

Participants undergo either flexible ureteroscopy or semi-rigid ureteroscopy to treat upper ureteric stones using holmium laser lithotripsy.

1 treatment visit and follow-up visits up to 3 months

Trial Site Locations

Total: 1 location

1

Assiut Hospital

Asyut, Asyut Governorate, Egypt

Actively Recruiting

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Research Team

O

Omar Ahmed Hamada Ali

M

Mohamed Ragab Abdallah, Doctor

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Published Research Related To This Trial