Ureteroscopy and stones: Current status and future expectations.
Anna E Wright, Nicholas J Rukin, Bhaskar K Somani
https://pubmed.ncbi.nlm.nih.gov/25374818Actively Recruiting
Led by Assiut University · Updated on 2025-11-25
100
Participants Needed
1
Research Sites
13 weeks
Total Duration
Researchers are evaluating the effectiveness, safety, success rates, operation times, and cost differences between flexible ureteroscopy and semirigid ureteroscopy for treating upper ureteric stones smaller than 2 cm. The study focuses on determining which patients with upper third ureteric stones can be treated with semirigid ureteroscopy and which require flexible ureteroscopy, considering factors such as stone size, stone impaction, ureter anatomy, surgeon experience, anesthesia, and ureteric dilation. Participants receive either flexible ureteroscopy or semirigid ureteroscopy, both minimally invasive procedures to remove stones from the upper ureter. Flexible ureteroscopy allows more maneuverability and access to difficult stone locations, while semirigid ureteroscopy is typically faster and less costly but may be less effective for complex cases. Both use holmium laser lithotripsy to break the stones. Treatment choice depends on stone location, size, surgeon preference, and equipment availability. During the study, participants will be monitored for stone-free status at 3 months post-procedure, along with assessments of safety, operation time, and cost-effectiveness. Researchers will track operative success and complications to compare outcomes between the two methods. The study involves regular follow-ups to evaluate treatment success and ensure patient safety throughout the trial period.
CONDITIONS
Flexible vs Semi-rigid URS
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Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Single procedure with follow-up over 3 months
Participants undergo either flexible ureteroscopy or semi-rigid ureteroscopy to treat upper ureteric stones using holmium laser lithotripsy.
1 treatment visit and follow-up visits up to 3 months
Total: 1 location
1
Assiut Hospital
Asyut, Asyut Governorate, Egypt
Actively Recruiting
O
Omar Ahmed Hamada Ali
M
Mohamed Ragab Abdallah, Doctor
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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Anna E Wright, Nicholas J Rukin, Bhaskar K Somani
https://pubmed.ncbi.nlm.nih.gov/25374818