Generation R Next Study on Improving Pregnancy and Child Outcomes Through Lifestyle, Nutrition, and Stress Management in Early Pregnancy and Preconception

What this Trial Is About

This research aims to improve birth and long-term outcomes for mothers and children by focusing on lifestyle, nutrition, and stress management during the preconception period and early pregnancy. The trial evaluates whether an intervention that optimizes these factors in both women and their partners can lead to better health outcomes. It is a randomized controlled trial embedded within the Generation R Next research infrastructure. Participants first receive an individual lifestyle consultation. Then, depending on the study group, they either receive standard care alone or standard care plus a lifestyle program. The lifestyle program includes three group sessions one physical and two online and access to a digital platform, focusing on healthy weight, stopping harmful habits, proper supplementation, a balanced diet, and stress reduction through mind-body therapies like yoga and mindfulness. Throughout the study, researchers will monitor birth outcomes such as preterm birth, birth weight, and Apgar scores. They will also assess adherence to lifestyle advice, sleep patterns, stress experience, social support, pregnancy weight changes, and child development up to 12 months after birth. Participants are encouraged to follow the lifestyle recommendations, and the study follows them from preconception or early pregnancy until one year after childbirth.

Generation R Next - Optimaal Opgroeien