Actively Recruiting
Genetic Architecture of Acute Aortic Syndromes and Aortic Aneurysm.
Led by University Hospital, Basel, Switzerland · Updated on 2025-05-16
730
Participants Needed
1
Research Sites
246 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this study is to explore the genetic information associated with the development of TAA and aAD in individuals without history or syndromic features (Marfan syndrome, Ehlers-Danlos syndrome, Turner syndrome etc.) for aortic disease. For this purpose, whole genome sequencing will be performed in patients with documented aortic aneurysm or/and aortic dissection.
CONDITIONS
Official Title
Genetic Architecture of Acute Aortic Syndromes and Aortic Aneurysm.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults over 18 years who had surgery for acute aortic dissection or thoracic aortic aneurysm at University Hospital Basel from 2015 onward
- Patients scheduled for surgery for acute aortic dissection or thoracic aortic aneurysm at University Hospital Basel starting in 2024
You will not qualify if you...
- Inability or unwillingness to provide informed consent
- Diagnosed heritable vascular disorders such as Marfan syndrome, Turner syndrome, Loeys-Dietz syndrome, or Ehlers-Danlos syndrome
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University Hospital Basel
Basel, Switzerland, 4031
Actively Recruiting
Research Team
D
Denis Berdajs, Prof. Dr.
CONTACT
I
Islam Salikhanov, Dr.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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