Actively Recruiting
Genotype-Phenotype Correlations in Patients With Alport Syndrome
Led by Xinhua Hospital, Shanghai Jiao Tong University School of Medicine · Updated on 2021-07-01
8165
Participants Needed
1
Research Sites
521 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Alport syndrome (AS) is caused by pathogenic variants in the type IV collagen genes COL4A3, COL4A4, and COL4A5. This study aims to enroll families and patients with a history of renal hematuria in 27 hospitals and detect these three genes for AS screening. This study also aims to analysis the effect of COL4A3/COL4A4/COL4A5 genotype on the development of kidney disease.
CONDITIONS
Official Title
Genotype-Phenotype Correlations in Patients With Alport Syndrome
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age up to 99 years (children, adults, older adults)
- All sexes are eligible
- Families and patients with a history of renal hematuria
- Signed informed consent to participate
You will not qualify if you...
- Diagnosis of polycystic kidney disease or hypertensive nephropathy
- Kidney biopsy showing other primary or secondary kidney diseases excluding type IV collagen-related kidney disease, including IgA nephropathy, membranous nephropathy, lupus nephritis, etc.
- Incomplete medical history or clinical data
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
China Xinhua Hospital, Shanghai Jiao Tong University School of Medicine.
Shanghai, China
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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