Actively Recruiting
GLP-1RA Effects on Lean Mass and Bone Health in Midlife Women
Led by University of Kansas Medical Center · Updated on 2026-02-20
50
Participants Needed
1
Research Sites
71 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is designed with the interest to learn on the effects of estrogen levels and how it affects body compositions and muscle function in midlife women who are taking a GLP-1RA for weight loss.
CONDITIONS
Official Title
GLP-1RA Effects on Lean Mass and Bone Health in Midlife Women
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female gender
- Age between 35 and 60 years
- Body mass index (BMI) of 30 or higher, or BMI of 27 or higher with at least one cardiometabolic risk factor (dyslipidemia, hypertension, obstructive sleep apnea, metabolic syndrome, fatty liver, polycystic ovary syndrome)
- Newly prescribed a GLP-1 receptor agonist medication
- English speaking
- Stable body weight for the past 6 months
You will not qualify if you...
- Pregnant women
- Under 35 years or over 60 years old
- Born male
- Unable to provide informed consent
- Cannot read or speak English
- Diagnosis of type 2 diabetes
- Discontinued GLP-1 receptor agonist medication less than 6 months ago
- Contraindications to GLP-1 receptor agonist use, including personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia type 2, pancreatitis, pregnancy, drug hypersensitivity, or active suicidal thoughts
- Currently taking aromatase inhibitors or selective estrogen receptor modulators (SERMs)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The University of Kansas Medical Center
Kansas City, Kansas, United States, 66160
Actively Recruiting
Research Team
J
Johanna Finkle, MD
CONTACT
H
Holly Hull, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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