Racial and ethnic disparities in disease activity and function among persons with rheumatoid arthritis from university-affiliated clinics.
J L Barton, L Trupin, D Schillinger...
https://pubmed.ncbi.nlm.nih.gov/21671414/Actively Recruiting
Led by Weill Medical College of Cornell University · Updated on 2026-01-22
250
Participants Needed
1
Research Sites
N/A
Total Duration
This research aims to find out if peer coaching can lower anxiety and depression in adults diagnosed with Rheumatoid Arthritis RA. It compares the effect of peer coaching, delivered by individuals who also have RA, to coaching from people without RA who discuss general health topics. The study focuses on whether anxiety and depression improve six months after the coaching sessions. Participants will be randomly assigned to one of two groups. One group receives nine weekly telephone sessions with a peer coach who uses techniques from cognitive behavioral therapy CBT, mindfulness, and exercise to address chronic pain and related issues. The other group receives nine telephone sessions with a coach who does not have RA and covers general health topics like nutrition and cancer awareness without using CBT or mindfulness. Sessions occur over 9 to 12 weeks, and data is collected multiple times during and after the intervention. Participants will complete surveys before starting, midway through, and at several timepoints after the sessions, including 3 weeks, 6 months, 12 months, and 24 months post-intervention. Researchers will measure changes in anxiety and depression using validated tools PHQ-8 and GAD-7. Other assessments include pain interference, sleep disturbance, physical function, social isolation, stress, loneliness, and quality of life. The study monitors these outcomes to understand the impact of coaching on mental well-being in people with RA.
CONDITIONS
Healthier: Health Coaching for People With Rheumatoid Arthritis to Improve Mental Well-Being
I
Iris Navarro-Millán, MD, MPH
S
Sarah Young, PhD
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Weill Medical College of Cornell University
Lead Sponsor
Bristol-Myers Squibb
Collaborating Sponsor
This table compares participation in this trial with other options available for this condition. The information is drawn from published research and the trial’s study details and is provided for educational purposes only.
| Factors | Peer coaching (Healthier) | General health coaching (Healthy Horizons) | Guideline‑recommended psychological support |
|---|---|---|---|
| What it is | Behavioral peer‑led coaching combining CBT, mindfulness and exercise support delivered by individuals with RA experience | Telephone coaching on general health topics by coaches without RA experience | Psychological interventions such as CBT are supported for depression and anxiety in people with RA by systematic reviews |
| Role in trial | Investigational behavioral intervention arm | Active comparator arm delivering general health coaching | Represents current guideline‑recommended care for mental health in RA beyond trial arms |
| Primary use or purpose | Support mental well‑being and reduce depression/anxiety in people with RA through peer coaching | Deliver general health education without focus on RA‑specific mental well‑being | Treat depression and anxiety in RA using evidence‑based psychological therapy |
| How it is given or performed | Delivered via peer coaches engaging using CBT, mindfulness and exercise components | Delivered by telephone by coaches without RA, covering general health topics in nine sessions | Typically delivered by mental health professionals through structured psychological therapy |
| Evidence status | Efficacy under investigation; no published results yet | Effectiveness under evaluation; no published data yet | Moderate to strong evidence supports psychological interventions improving mood and pain outcomes in RA |
| Important limitations | No prior efficacy data; impact of peer background and intervention components unknown | General health content may not target depression or RA‑specific mental health needs | Most evidence comes from structured therapies by professionals; peer‑delivered coaching may differ in effectiveness |
Disclaimer: This comparison is created with the help of artificial intelligence(AI) and may contain errors or missing information. It is not medical advice and does not mean one option is better or safer than another. Clinical trials are still being studied, and joining a trial is your choice. Please consult your healthcare professional before making any decisions.
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 screening and enrollment visit (telephone or online)
Duration - 9 to 12 weeks
Participants receive 9 telephone-delivered health coaching sessions over 9 to 12 weeks, either from a peer coach with rheumatoid arthritis or a coach with another chronic condition.
9 telephone sessions
Duration - Up to 24 months post-intervention
Participants are followed up for ongoing assessment of mental well-being and other outcomes for up to 24 months after completing the coaching intervention.
Assessments at 3 weeks, 6 months, 12 months, and 24 months post-intervention
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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Lead Sponsor
Bristol-Myers Squibb
Collaborating Sponsor