Study of Different Height Measurement Methods to Reduce Lung Injury Risk in Adults with Acute Respiratory Distress Syndrome on Mechanical Ventilation

What this Trial Is About

This research investigates how different height measurement methods impact the risk of ventilator-induced lung injury VILI in patients with acute respiratory distress syndrome ARDS. ARDS causes uneven lung injury, with some lung areas collapsed and others aerated, known as the baby lung. Mechanical ventilation is essential but can worsen lung injury if tidal volumes are not set properly. Since predicted body weight PBW used to set tidal volume depends on height measurement, inaccuracies from common height measurement methods could increase lung stress and injury in these patients. During the study, patients will have their height measured using five methods stadiometer, visual estimation, tape measurement, infrared laser, and heel-to-knee distance. For each height, PBW and a tidal volume of 6 mLkg PBW will be calculated and applied in random order, each for 30 minutes. Before each tidal volume period, a short alveolar recruitment maneuver will standardize lung volume. Researchers will assess lung stress, ventilatory mechanics, gas exchange, and regional ventilation distribution using electrical impedance tomography, while continuously monitoring hemodynamics and oxygenation. Participants will be involved for approximately two hours. During this time, ventilatory parameters such as plateau pressure, driving pressure, and transpulmonary pressures will be recorded. The study focuses on measuring pulmonary stress related to different height measurements without any follow-up. This research aims to clarify whether height measurement methods significantly affect lung mechanics and injury risk in ARDS patients receiving mechanical ventilation.

Height Measurement Procedures Influence the Risk of Ventilator-induced Lung Injury in ARDS