Actively Recruiting
High Definition Transcranial Direct Current Stimulation (HD-tDCS) for Early Alzheimer's Disease
Led by Anhui Medical University · Updated on 2025-07-11
60
Participants Needed
1
Research Sites
287 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To investigate the clinical effect neural mechanism of high-definition transcranial direct current stimulation combined with cognitive training on early AD
CONDITIONS
Official Title
High Definition Transcranial Direct Current Stimulation (HD-tDCS) for Early Alzheimer's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with early Alzheimer's disease or related diseases according to NINCDS-ACDRADA criteria
- Mini-Mental State Examination (MMSE) score between 10 and 27
- Clinical Dementia Rating (CDR) score less than or equal to 2
- Under treatment with acetylcholinesterase inhibitors for at least 3 months
- Psychotropic treatments allowed if stable and unchanged for at least 3 months
You will not qualify if you...
- Clinical Dementia Rating (CDR) score greater than 2
- History or signs of severe psychiatric illnesses such as major depression, psychosis, or obsessive compulsive disorder
- History of head injury, stroke, or other neurological diseases
- Presence of organic brain defects on T1 or T2 imaging
- History of seizures or unexplained loss of consciousness
- Having implanted pacemaker, medication pump, vagal stimulator, or deep brain stimulator
- Family history of medication refractory epilepsy
- History of substance abuse within the last 6 months
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Anhui Medical University
Hefei, Anhui, China, 230032
Actively Recruiting
Research Team
K
Kai Wang, PhD
CONTACT
X
Xingqi Wu, M.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
3
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